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One swab is enough.

Use of two throat swabs did not significantly improve the sensitivity of the OIA MAX test for group A streptococcus in a randomized study of 363 children aged 5-18 years with acute pharyngitis, said Elias N. Ezike, M.D., of the Children's Hospital of Michigan, Detroit, and his associates (Arch. Pediatr. Adolesc. Met. 2005;159:486-90).

One throat swab was obtained from a group of 117 children (group 1), and two swabs were obtained from a group of 186 children (group 2). The sensitivity was 94.7% and 100% for groups 1 and 2, respectively, and the specificity was 92.4% and 96.3% for groups 1 and 2, respectively. Overall, the OIA MAX test identified group A streptococcus in 148 of the 363 (40.8%) patients, including 71 in group 1 (40.1%) and 77 in group 2 (41.4%). Clinical presentations were not significantly different between children with and without group A streptococcus, and there was no association between the severity of pharyngitis and the sensitivity of the OIA MAX test.

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Title Annotation:Clinical Capsules
Author:Splete, Heidi
Publication:Family Practice News
Article Type:Brief Article
Geographic Code:1USA
Date:Jun 15, 2005
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