One swab is enough.
Use of two throat swabs did not significantly improve the sensitivity of the OIA MAX test for group A streptococcus in a randomized study of 363 children aged 5-18 years with acute pharyngitis, said Elias N. Ezike, M.D., of the Children's Hospital of Michigan, Detroit, and his associates (Arch. Pediatr. Adolesc. Met. 2005;159:486-90).
One throat swab was obtained from a group of 117 children (group 1), and two swabs were obtained from a group of 186 children (group 2). The sensitivity was 94.7% and 100% for groups 1 and 2, respectively, and the specificity was 92.4% and 96.3% for groups 1 and 2, respectively. Overall, the OIA MAX test identified group A streptococcus in 148 of the 363 (40.8%) patients, including 71 in group 1 (40.1%) and 77 in group 2 (41.4%). Clinical presentations were not significantly different between children with and without group A streptococcus, and there was no association between the severity of pharyngitis and the sensitivity of the OIA MAX test.
|Printer friendly Cite/link Email Feedback|
|Title Annotation:||Clinical Capsules|
|Publication:||Family Practice News|
|Article Type:||Brief Article|
|Date:||Jun 15, 2005|
|Previous Article:||Reasons for vaccine refusal.|
|Next Article:||Group B strep poorly diagnosed.|