Printer Friendly

Oncogenes and cancer aggressiveness.

Oncogenes and cancer aggressiveness

The fate of children with neuroblastoma, a cancer of the nervous system, can be gauged by looking at how many copies of the responsible oncogene, or cancer-causing gene, are present in their tumor cells, says Garrett M. Brodeur of Washington University in St. Louis. Collaborating with laboratories across the United States, Brodeur found that 68 percent of children whose tumor cells had only one copy of the oncogone were likely to have been spared disease progression after 18 months. This compared with a 30 percent figure in children with three to 10 copies and no children with more than 10 copies. The presence of mutiple gene copies may somehow increase the aggressiveness of the tumor, he says.
COPYRIGHT 1985 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1985, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:neuroblastoma
Author:Silberner, Joanne
Publication:Science News
Date:Apr 20, 1985
Words:121
Previous Article:Look Mom, less risk.
Next Article:Timing key in cancer chemotherapy.
Topics:


Related Articles
Childhood cancer clue.
Exposing lung cancer as a genetic disease.
Cancer roadblock on cholesterol pathway.
Gene-tracking leads to Nobel Prize.
Gene discovery: key to colon cancer test.
Designing proteins to block cancer genes.
Diverse strategies to vanquish cancer: researchers take aim at malignancy.
Olfactory neuroblastoma.
Risk factor: throat cancer linked to virus spread by sex.
This trick boosts cancer's spread.

Terms of use | Copyright © 2016 Farlex, Inc. | Feedback | For webmasters