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Omega-3 supplements ease osteoarthritis pain in mice.

A study by Duke University researchers published in the Annals of the Rheumatic Diseases found that mice fed omega-3 fatty acid supplements had healthier joints than those fed diets high in saturated fats and omega-6 fatty acids, suggesting that certain dietary fats, and not simply body weight, can lead to osteoarthritis. *

Four-week-old mice were fed a low-fat diet or one of three high-fat diets: a diet high in saturated fat, a diet high in omega-6 fatty acids, or a diet high in omega-6 fatty acids plus a supplement of omega-3 fatty acids. At 16 weeks, the mice had surgery to induce osteoarthritis of the knee. The animals that ate an unhealthy high-fat diet developed severe arthritis and joint inflammation compared to mice fed the regular diet or the high-fat diet supplemented with omega-3 fatty acids.

"Our results suggest that dietary factors play a more significant role than mechanical factors in the link between obesity and osteoarthritis," said Farshid Guilak, senior study author.

Editor's Note: The researchers also tested the mice for how quickly small ear punch wounds healed. The wounds healed much more quickly in the mice given omega-3 fatty acids than they did in the mice that did not receive the supplement. Reference

* Ann Rheum Dis. 2014 Jul 10.

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Title Annotation:In The News
Publication:Life Extension
Article Type:Brief article
Geographic Code:1USA
Date:Nov 1, 2014
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