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Omega-3 fatty acids and the DHA principle.


Omega-3 fatty acids and the DHA principle.

Valentine, Raymond C. and David L. Valentine.

CRC Press


249 pages




DHA (docosahexaenoic acid) is an omega-3 fatty acid that enables biochemical processes in organic membranes, but also reduces proton barrier properties and increases the rates of lipid oxidation. This balancing of benefits and risks lead the authors (both affiliated with the Marine Science Institute at the U. of California at Santa Barbara) to propose the DHA principle, which "states that the blending of lipids to form cellular membranes is evolutionarily honed to maximize benefit while minimizing risk, and that a complex blending code involving conformational dynamics, energy stress, energy yield, and chemical stability underlies all cellular membranes." It is this blending code that is the subject of their book, which reviews the evolution, properties, and functions of omega-3s and other membrane lipids across a wide variety of organisms. They also address applications related to petroleum degradation, winemaking, global warming, molecular farming, and neurodegenerative diseases.

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Publication:SciTech Book News
Article Type:Brief article
Date:Jun 1, 2010
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