Printer Friendly

Now, faster, cheaper blood test to accurately diagnose asthma.

Washington, April 16 ( ANI ): Researchers have developed a faster, cheaper and more accurate tool for diagnosing even mild cases of asthma using just a single drop of blood.

The researchers used neutrophil cell function in a clinical study to show accurate asthma diagnosis.

To directly diagnose asthma, David Beebe, a UW-Madison professor of biomedical engineering and co-author on the paper, and his team focused on the cell function of neutrophils. Neutrophils are the most abundant white blood cell in the body and generally are the first cells to migrate toward inflammation.

"Neutrophils are sort of like a dog tracking something. They sense a chemical gradient, like an odor, in the body," Beebe says.

In other words, the human body emits chemical signals in response to inflammation or wounds and the neutrophils detect those chemical signals and migrate to the site of the wound to aid in the healing process. Researchers can track the velocity at which the neutrophil cells migrate - the chemotaxis velocity - to differentiate nonasthmatic samples from the significantly reduced chemotaxis velocity of asthmatic patients.

UW-Madison students have developed the kit-on-a-lid-assay (KOALA) microfluidic technology, which allows them to detect neutrophils using just a single drop of blood.

The KOALA diagnostic procedure uses simple lids and bases (each being a small, cheap piece of plastic), diagnosticians place a KOALA lid containing a chemical mixture onto the base containing the blood sample. That chemical mixture triggers neutrophil migration - and researchers can automatically track and analyze the neutrophil chemotaxis velocity using custom software.

The team has published online in the journal Proceedings of the National Academy of Sciences. ( ANI )

Copyright 2014 aninews.in All rights reserved. Provided by Syndigate.info , an Albawaba.com company
COPYRIGHT 2014 Al Bawaba (Middle East) Ltd.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2014 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:Asian News International
Date:Apr 16, 2014
Words:282
Previous Article:How electrical energy naturally produced at sea floor may have given rise to life.
Next Article:'Desperate' Pistorius made 'textbook mistakes' in witness stand: Experts.
Topics:

Terms of use | Copyright © 2017 Farlex, Inc. | Feedback | For webmasters