Novo Nordisk obtains United States patent.
Novo Nordisk A/S (Bagsvaerd, Denmark) has patented insulin precursors and insulin precursor analogs having a mini C-peptide comprising at least one aromatic amino acid residue have an increased folding stability. The insulin precursors and insulin precursor analogs can be expressed in yeast in high yields and are preferably not more 15 amino acid residues in length. Also provided are polynucleotide sequences encoding the claimed precursors or precursor analogs, and vectors and cell lines containing such polynucleotide sequences. (US 6,521,738)
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|Publication:||BIOTECH Patent News|
|Article Type:||Brief Article|
|Date:||Feb 1, 2003|
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