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Nocturnal dipping less common in black patients.

DETROIT -- African Americans tend to have blunting of the nocturnal decline in blood pressure that is seen in whites, a pattern that helps explain African Americans' in creased cardiovascular burden and risk for severe end organ damage, Dr. Addison Taylor said at a meeting sponsored by the International Society on Hypertension in Blacks.

Sustained nocturnal blood pressure, or "nondipping"--typically defined as having a less than 10% drop in nighttime blood pressure--has been observed in African Americans, compared with whites, in several studies but is not as apparent in non-American blacks.

The mechanisms remain unclear, but in studies, reduced or absent nocturnal dipping in both normotensive and hypertensive African Americans was associated with increased left ventricular mass index. The same was not true in whites, even when groups were matched for daytime mean blood pressure levels, and the nocturnal nondipping in African Americans remained even when the patient was treated for hypertension, said Dr. Taylor, professor of medicine, pharmacology, and physiology at Baylor College of Medicine, Houston.

End-organ damage reportedly has a stronger association with nighttime blood pressure than with daytime blood pressure, he noted.

Findings were similar in the triethnic Baylor study, on which Dr. Taylor was an investigator.

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Title Annotation:Cardiovascular Medicine
Author:Worcester, Sharon
Publication:Family Practice News
Article Type:Brief Article
Geographic Code:1USA
Date:Aug 15, 2004
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