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Nicotine receptor modulator ineffective in attention disorder.

In a pilot study, pozanicline (a medication made by Abbott), also known as nicotinic receptor partial agonist ABT-089, was found to be ineffective in adults with Attention-Deficit Hyperactivity Disorder (ADHD). In a previous study, the drug, given in dosages of 40 milligrams (mg.) per day and 40 mg. twice daily, had relieved symptoms of ADHD in adults; however, another study showed the same treatment to be ineffective in pediatric ADHD. Individuals with ADHD are more likely to smoke, and the severity of ADHD symptoms has been closely associated with increased smoking. During this study, however, no change in smoking habits was observed during active treatment.

(Sources: American Academy of Child and Adolescent Psychiatry, 2011; 50:73-78; Psychopharmacology, 2012; 219:715-725; and Journal of Clinical Psychiatry, June 2012.)
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Publication:Nutrition Health Review
Date:Dec 22, 2011
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