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Neurocrine Biosciences Inc.

NEUROCRINE BIOSCIENCES INC. (San Diego CA) said an experimental depression drug it was developing with GlaxoSmithKline Plc (London GBR) failed in a mid-stage trial to work better than a placebo. Neurocrine said it plans to meet with Glaxo in the coming months to determine the next steps for the depression program. The Phase 2 trial, which involved 150 patients experiencing a major depressive episode, found no benefit for patients treated with the experimental drug, a corticotropin releasing factor (CRF1) receptor antagonist called GSK561679. Three separate academic collaborative clinical trials are ongoing to evaluate the effects of GSK561679 in post traumatic stress disorder, anxiety and alcoholism.

Shares of Neurocrine Biosciences closed the week up 4 cents at $5.74 on Nasdaq.
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Title Annotation:CORPORATE
Publication:MondayMorning
Date:Sep 20, 2010
Words:120
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