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Nanotubes used to detect tumor cells, map lymph nodes.

Biomedical researchers at the University of Arkansas at Fayetteville and University of Arkansas for Medical Sciences in Little Rock have developed a special contrast-imaging agent that is capable of molecular mapping of lymphatic endothelial cells and detecting cancer metastasis in sentinel lymph nodes.

The new material could be used as a more efficient and less toxic alternative to nanoparticles and fluorescent labels used in the non-invasive, targeted molecular detection of normal ceils, such as immune-related cells, and abnormal cells, such as cancer cells and bacteria. Findings were published in Nature Nanotechnology.

Research teams led by Jin-Woo Kim, associate professor in the department of biological and agricultural engineering at the University of Arkansas, and Vladimir P. Zharov, professor at the Winthrop P. Rockefeller Cancer Institute at UAMS, worked with carbon nanotubes and gold. In a previous study, Kim and Zharov demonstrated that carbon nanotubes held great promise as contrast agents for photoacoustic detection and photothermal killing of individual bacteria in blood systems.
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Title Annotation:Innovation News
Publication:Arkansas Business
Date:Sep 7, 2009
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