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Nanotoxicity of CdSe quantum dots on peripheral nerve cells.

Semiconductor nanocrystals, also known as quantum dots are a nontraditional semiconductor with unique size-dependent properties that are of great interest across many industries. Researchers are exploring their applications in many fields such as optoelectronic and photovoltaic devices, optical amplifier media, probing, and imaging. With such explosion of application research, however, the effect of these nanocrystals to human health and the environment is essential unknown; the guideline of safety handling and disposal is nonexisting.

In this study, we are attempting to establish the baseline toxicity of one of the most common semiconductor nanocrystals, CdSe quantum dots (QDs), on the peripheral nerve system by employing the QDs directly on the dorsal root ganglia (DRG) neurons of rats. Observations of cell morphology and MTT colorimetric assay are the procedures of toxicity evaluation.

Key words: quantum dots, MTT, DRG neuron, toxicity

Briana M. Lindberg (1), Wenjuan Gao (2), James C.K. Lai (3), Solomon W. Leung (4)

(1) Corresponding author, Civil & Environmental Engineering Department, Idaho State University, Pocatello, ID 83209, USA Fax: 208-282-4538; tel: 208-2822524; email: Iindbri3@isu.edu

(2) Civil & Environmental Engineering Department, Idaho State University, Pocatello, ID 83209, USA Fax: 208-282-4538; tel: 208-282-2524; email: gaowenj@isu.edu

(3) Biomedical and Pharmaceutical Sciences Department and Biomedical Research Institute, Idaho State University, Pocatello, ID 83209, USA Fax: 208-282-4305; tel: 208-282-2275; email: lai@pharmacy.isu.edu

(4) Civil & Environmental Engineering Department and Biomedical Research Institute, Idaho State University, Pocatello, ID 83209, USA Fax: 208-282-4538; tel: 208-282-2524; email: leunsolo@isu.edu

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Title Annotation:56TH ANNUAL SYMPOSIUM OF THE IDAHO ACADEMY OF SCIENCE: THEME: ENERGY, MATERIALS, AND NANOTECHNOLOGY
Author:Lindberg, Briana M.; Gao, Wenjuan; Lai, James C.K.; Leung, Solomon W.
Publication:Journal of the Idaho Academy of Science
Article Type:Report
Geographic Code:1USA
Date:Dec 1, 2014
Words:245
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