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Myocarditis rare in influenza. (Clinical Capsules).

The prevalence of myocarditis during influenza infection is lower than previously estimated, while the prevalence of skeletal muscle injury is much higher, said Dr. Kim Greaves of St. Bartholomew's Hospital, London, and associates.

Estimates that influenza-related myocarditis affects up to 10% of influenza patients have been based on nonspecific findings, such as cardiac symptoms and ECG abnormalities. But nonspecific findings such as ST-segment changes could have been caused by respiratory alkalosis from an increased ventilation rate or fever-induced tachycardia.

In a recent study, researchers estimated the prevalence of influenza-related myocarditis using measures of cardiac troponins and creatine kinase, which are more specific markers of myocardial injury The study, involving 152 influenza patients at 60 U.S. medical centers, showed no evidence of myocardial injury (Arch. Intern. Med. 163:165-68, 2003).
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Author:Ann Moon, Mary
Publication:Internal Medicine News
Article Type:Brief Article
Date:Apr 1, 2003
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