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Mutation causing cleft palate found.

Mutation causing cleft palate found

Another study that could be a research springboard into thebroad arena of genetic disorders has been completed by research groups at the University of London, the Whitehead Institute for Biomedical Research in Cambridge, Mass., and the National University Hospital in Reykjavik, Iceland. In the March 5 NATURE, the scientists report that they have localized the gene mutation causing cleft palate.

The genetic defect, assayed in a large family in Iceland,appears to be linked to the X chromosome, say the scientists. Because cleft palate develops during the stage of embryo development associated with disorders like spina bifida, closer analysis of the newly identified gene mutation may elucidate the mechanism of other developmental abnormalities.
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Publication:Science News
Date:Mar 21, 1987
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