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Muscle Fiber Distribution of the Soft Palate in Patients with Obstructive Sleep Apnea Syndrome.

It has been suggested that the alterations in morphologic features of the pharynx may be an important factor in the pathogenesis of obstructive sleep apnea syndrome (OSAS). In this investigation, pharyngeal tissue was obtained from three apneic patients in an attempt to detect a trend between muscle fiber distribution and the severity of OSAS. Specimen muscle fibers were analyzed for fiber type histochemically and analyzed for distribution using a quantitative technique. Once these distributions of muscle fiber types were known, they were compared to the preoperative polysomnograms which indicate the actual severity of OSAS. Preliminary results suggest that there is not a trend between the dispersion of type I and type IIA fiber areas and the severity of OSAS, due to limited sample size. These results will serve as a foundation for further studies.
Meredith Alger
South Carolina Governor's School for Science and Mathematics
COPYRIGHT 2001 South Carolina Academy of Science
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2001 Gale, Cengage Learning. All rights reserved.

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Author:Alger, Meredith
Publication:Bulletin of the South Carolina Academy of Science
Article Type:Brief Article
Geographic Code:1U5SC
Date:Jan 1, 2001
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