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Most compact MS for liquids.

The major components Of a mass spectrometry (MS) system are the inlet, ion source, mass analyzer, ion detector, vacuum system, electronics, and computer. Different inlets are used for gases, solids, and liquids, and a quadrupole mass spectrometer adds rods placed in parallel to filter ions.

This well-established architecture has recently been recreated for the first time in a microelectromechanical system (MEMS) based on silicon engineering technology. With the first commercialized MS technology on a chip, the Microsaic 3500 MiD, developed by Microsaic Systems plc, Woking, U.K., is the most compact mass spectrometer for liquid analysis.

Within a vacuum chamber at the center of the system sits a userreplaceable module that contains the ionchip, a silicon quadrupole filter. At the front of the chamber is the vac-chip, a silicon-based module that provides the interface between the room conditions and the chamber, so that ions can enter while most of the neutral molecules from the background air are kept out. Connected to the vacuum entrance on the front panel is a module containing the spraychip, another microengineered part within which the ionized spray is produced. Just one-third the size of typical MS systems, the 3500 MiD uses less solvent and just 10% of the power.

Microsaic Systems plc, www.microsaic.com

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Title Annotation:Analytical Instruments; Microsaic 3500 MiD developed by Microsaic Systems plc
Comment:Most compact MS for liquids.(Analytical Instruments)(Microsaic 3500 MiD developed by Microsaic Systems plc)
Publication:R & D
Article Type:Brief article
Geographic Code:4EUUK
Date:Sep 1, 2012
Words:210
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