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Mitral annulus calcification doubles CV deaths: NHLBI-sponsored study. (cardiovascular, National Heart, Lung, and Blood Institute).

Las Vegas -- Mitral annulus calcification is associated with a doubling of cardiovascular mortality risk in the elderly, Dr. Eddy Barasch reported at the annual meeting of the American Society of Echocardiography.

Dr. Barasch, of St. Francis Hospital in Roslyn, N.Y., reported on 3,929 participants in the Cardiovascular Health Study, a National Heart, Lung, and Blood Institute-sponsored prospective longitudinal study of community-dwelling seniors. The mean age of participants was 76 years; 64% were women. Baseline echocardiograms obtained in the mid-1990s showed no aortic stenosis in participants, who were also free of cardiovascular disease at baseline.

During a mean 6.2 years of follow-up, there were 472 deaths, including 163 from cardiovascular disease. The risk of cardiovascular death among 1,102 study participants with mitral annulus calcification was elevated 2.1-fold.

In contrast, participants with aortic annulus calcification or aortic sclerosis had no increased risk of either cardiovascular or all-cause mortality, according to Dr. Barasch.
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Title Annotation:Cardiovascular Medicine
Author:Jancin, Bruce
Publication:Internal Medicine News
Article Type:Brief Article
Date:Nov 15, 2003
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