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Changes in Gait Can Predict Decline in Memory and Thinking. A study by researchers from the Mayo Clinic found that certain factors involved in a person's gait can predict declines in memory and thinking. The study involved 3,426 cognitively normal participants between ages 70 and 89. The researchers used gait criteria, such as stride length, ambulatory time, gait speed, step count, cadence, stance time, and arm swing. Changes in some of these factors are linked with memory decline, thinking and language skills, and spatial relationships. The researchers used computerized analyses to measure the gait parameters, which could detect gait changes before standard neuropsychological testing could detect cognitive impairment. Using the computer analysis is a noninvasive test to identify patients at high risk for cognitive decline and target appropriate treatment, says lead author Rodolfo Savica, MD. The study was published online in the Journal of Alzheimer's Disease Nov. 19, 2016.

Protein in Urine Linked to Dementia Risk. Kidney dysfunction, characterized by protein in urine, among other risk factors, may lead to memory and thinking problems and possibly even dementia, according to a meta-analysis that involved 27, 805 participants. The analysis found that people with the protein in their urine were 35 percent more likely to develop cognitive impairment or dementia. Other risk factors that kidney disease and dementia have in common include cardiovascular disease, stroke, type 2 diabetes, and systolic hypertension, among others.

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Title Annotation:MIND & MEMORY
Publication:Duke Medicine Health News
Article Type:Brief article
Date:Feb 1, 2017
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