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Micronutrients and health - molecular biological mechanisms. (Bookshelf).

Edited by Kalanithi Nesaretnam

Lester Packer

Published 2001 Hardback 404 Pages

Price: [pounds sterling]140.00

(USA: American Oil Chemists' Society)

A workshop on Micronutrients and Health: Molecular Biological Mechanisms, brought together a small but select number of experts with a special interest in micronutrients, molecular mechanisms, and the effects of oxidants and antioxidants on health. Research in these areas is experiencing unprecedented interest throughout the world in the fields of nutrition, biochemistry, molecular biology, medicine, agriculture, public health, and biotechnology, with important implications for human health and lifestyle.

The meeting was held in July 2000, and brought together more than 200 researchers to discuss the latest developments in molecular aspects of nutrition and the role of free radicals. This volume brings together the presentations given. Among the contributors were leading authorities in the field of antioxidant nutrition from the region as well as other parts of the world.

Chapter Titles: Oxidative damage, antioxidants and human sperm; The ferric reducing (antioxidant) power (FRAP) assay, and antioxidants in the Chinese diet and population; Oxidant damage in haptoglobin knockout mouse; Study on antioxidative capacity of flavonoids from dried balsam flowers; Antioxidant action of curcumin; Free radical reaction of green tea polyphenols; Modulation of the peroxyntrite-scavenging activity of antioxidants by physiologic concentrations of bicarbonate; Antioxidant and prooxidant effects of [beta]-carotene and lycopene on oxidant-induced damage in Hs68 cells; Free radical scavenging and antigenotoxicity: mechanisms of cancer chemopreventive effects of plant polysaccharides; Efficacy of natural and synthetic antioxidants in RBD palm olein by differential scanning calorimetry; Modulation of apoptosis by superoxide radical; Aerobic glycotysis by proliferating cells - a protective strategy against reactive oxygen species; Saponin from schefflera odorata as potential modulator of the cell- signalling pathways; Accelerated cellular senescence and altered response to nitric oxide (NO) in glucose-6-phosphate dehydrogenase (G6PD)-deficient human fibroblasts; Increase of mitochondrial mass and mitochondrial DNA content as a response to oxidative stress of human cells harboring mitochondrial DNA mutation; MAP kinase activation and environmental stress; Regulation of the degradation of oxidised proteins; Glutathione depletion induces giant DNA fragmentation associated with apoptosis or necrosis; Gingko biloba extract and gene expression; Conjugated linolenic acid: anticancer effects; Molecular aspects of age-related macular degeneration in humans; Antiepileptic mechanism of zonisamide involves its antioxidant effect in the brain; Determination of antioxidant effects by ESR-CT imaging of rat brain tissue damage formed during iron-induced epileptogenesis in rats; Extreme longevity: the role of antioxidant enzymes, vitamins and micronutrients; Mechanisms of cholesterol - or Homocysteine - induced atheros clerosis: role of vitamin E; Biomarkers of oxidative stress and of antioxidative defence: relationship to intervention with antioxidant-rich foods; Redox regulation of antioxidant protection of the heart; Imbalanced antioxidant status in transfusion-dependent thalassemia patients in Jakarta, Indonesia; Red palm oil, vitamin A, and the antioxidant enzymes; Effect of flavonoids and trace elements on murine immune response; Antibodies of all isotypes to oxysterols in normal human sera: a parameter for in vivo oxidative status?; Tocopherol and tocotrienol effects on normal mammary epithelial cell growth and apoptosis; Y- vs. [partial]-Tocopherol-rich edible oils and their relevance for low density lipoprotein oxidation in humans; Effect of tocotrienols on estrogen metabolism in MCF-7 and MDA-MB231 human breast cancer cell lines; Antioxidants modulate the course of carotid antherosclerosis: a four year report; Human vitamin E requirements: is [partial]-tocopherol the only form that is required?; Oxidative damage i nduced by peroxynitrite/singlet oxygen in rat liver mitochondria and its inhibition by tocotrienols from palm oil
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Publication:Food Trade Review
Article Type:Brief Article
Date:Oct 1, 2001
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