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Microfluidic chip aids PET imaging.

Positron emission tomography (PET) has remained a powerful technique for the detection of diseases such as cancer, Alzheimer's and cardiovascular disease. Now researchers at UCLA, the California Institute of Technology, Stanford Univ., Siemens, and Fluidigm have offered up a tool to aid in PET imaging schemes.

Traditionally, PET employs a labeled version of the sugar glucose, called fluorodeoxyglucose (FDG). For their part, the research team has demonstrated that FDG could be synthesized on a "stamp-size" microfluidic chip. These chips have a design very similar to integrated circuits except they consist of fluid channels, chambers, valves, and switches that can carry out chemical operations to synthesize and label molecules for PET imaging. All of the operations of the chip can subsequently be controlled by a PC.

The goal, according to UCLA, will be to one day integrate these new chips into a small control device operated by a PC that will be commercially productized and distributed to hospitals, universities, and pharmaceutical companies looking to produce whatever molecules they choose for PET molecular imaging.

UCLA www.ucla.edu, 310-825-4321

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Title Annotation:MICRONANO; Positron emission tomography
Publication:R & D
Article Type:Brief Article
Geographic Code:1USA
Date:Jan 1, 2006
Words:177
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