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Microcalorimetry of macromolecules; the physical basis of biological structures.

9781118104514

Microcalorimetry of macromolecules; the physical basis of biological structures.

Privalov, Peter L.

John Wiley & Sons

2012

393 pages

$139.95

Hardcover

Wiley series in protein and peptide science

QP801

Privalov (biology, biophysics, Johns Hopkins University) reviews basics of the thermodynamics of calorimetry and explains how calorimetry is used in thermodynamic studies of macromolecules. The book begins by offering relevant physicochemical info on the aqueous solutions of organic compounds, then describes calorimetric techniques used for thermodynamic studies of biological macromolecules and gives advice on how to use these techniques in experiments with proteins, nucleic acids, and their complexes. One chapter focuses on thermodynamic problems related to the structures of proteins and nucleic acids. The rest of the book considers the results of calorimetric studies of various types of biological macromolecules and their complexes; these studies have led to the reconsideration of widely accepted dogma on the roles of hydrogen bonding, hydrophobic interactions, and water in the formation of macromolecular structures.

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Publication:Reference & Research Book News
Article Type:Book review
Date:Oct 1, 2012
Words:166
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