Merger creates super-college.
Handsworth College and East Birmingham College at Garretts Green will join forces to become the third largest college in Britain.
From August 1, the new college - which have 80 sites across the city - will be known as City College, Birmingham.
Handsworth College principal Mr Chris Webb becomes City College chief executive and accounting officer, while East Birmingham head Mr Tony Henry will be academic principal.
Mr Webb said there would be no redundancies and the merger would create more opportunities for the 400 fulime lecturers.
City College will handle more than 40,000 students every year.