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Men Continue Taking Testosterone Despite Known Heart Dangers.

Supplemental testosterone use by men with age-related testosterone deficiency may increase the risk of heart attack and stroke without improving symptoms. Despite these dangers, a study published online Dec. 28, 2018, in JAMA Internal Medicine found that men with coronary artery disease (CAD) continue to use testosterone "off label"--that is, in an unapproved fashion. A group of researchers examined Medicare data on millions of U.S. men ages 50 and older (average age 71.2) from 2007 to 2016 and compared testosterone prescriptions written for on-label and off-label use. They found these prescriptions reached a high in 2013 when written for 3.2 percent of men who received a CAD diagnosis that year and 2.4 percent of those who did not have CAD. Regional variations ranged from 0.5 percent to 7.0 percent. Despite elevated cardiovascular risk without proven benefit, testosterone prescriptions cost Medicare $108 million in 2017, a figure that rose to $402 million in 2016.

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Title Annotation:HEART BEAT
Publication:Heart Advisor
Date:Feb 22, 2019
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