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Melatonin improves bone density.

A study published in the Journal of Pineal Research of postmenopausal women with osteopenia has shown that long-term treatment with melatonin, which naturally decreases in the body with age, can improve the density of bone at the neck of the femur, in proportion to the level of treatment. *

In the trial, researchers gave 81 healthy postmenopausal women with osteopenia, aged 56 to 73, nightly doses of 1 or 3 mg of melatonin or a placebo, and measured them at the beginning of the trial and after a year. "We were looking at body composition and, at the spine and hip, bone mass density," said lead researcher Dr. Anne-Kristine Amstrup. Biochemical markers of calcium homeostasis were also measured throughout the trial.

"Compared with the women taking the placebo, those on the 1 mg dose experienced a bone mass density increase of 1.4% at the neck of the femur," added Dr. Amstrup. "Those on the higher dose experienced an increase of 2.3%. The treatment did not affect bone mass density elsewhere, nor bone turnover."

Editor's Note: The study also found that the melatonin treatment helped study participants lose fat (almost 7% over the course of the year) while gaining lean tissue instead.

Reference

* J Pineal Res. 2015 Jun 3.

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Title Annotation:In The News
Publication:Life Extension
Article Type:Brief article
Date:Oct 1, 2015
Words:209
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