Market profile: GC-MS in food analysis.
GC-MS has developed into a common analytical technique in the agriculture and food industries due to its ability to separate and clearly identify many of the compounds of interest. Despite the improvements in single quadrupole and time-of-flight GC-MS instruments, they lack the MS/MS capabilities found only in ion trap GC-MS instruments. Such capabilities are necessary when dealing with complex food matrices and harder to identify contaminants. However, a number of triple quadrupole GC-MS instruments have recently been introduced, or will be introduced within the next few months. Such configurations combine the strength of MS/MS for identification confirmation with the sensitivity of quadrupole mass analyzers.
GC-MS is used for the detection and analysis of pesticide residues mostly in fruits and vegetables. Although LC-MS is also used for such analyses, most of the more recently developed pesticides are designed to breakdown more rapidly, and have lower molecular weights, which generally makes them more suited to gas phase separations.
The contamination of pet food and milk products with melamine has garnered considerable media attention in the past year. The spiking of such products with melamine is intended to trick conventional food analysis methods, such as the Kjeldahl method, that test for nitrogen levels, but cannot differentiate between organic nitrogen and melamine-based nitrogen. GC-MS, on the other hand, can specifically identify the presence of melamine. While analytical work-arounds are being developed to address melamine, GC-MS offers the specificity to be able to identify a wide range of food contamination problems that could arise. There are also developments in LC-MS for melamine identification.
Although Agilent Technologies is by far the leading vendor in the GC-MS food analysis market, the top five vendors, which also include Thermo Fisher Scientific, Shimadzu, Varian and PerkinElmer, also have quite a strong presence in food analysis. Combined, these five vendors account for around 80% of the market. The worldwide market for GC-MS in food analysis is expected to be more than $90 million in 2008 (including both GC and MS portions), and should see mid-single digit growth in demand, thanks in large part to timely issues such as melamine.
GC/MS in Food Testing at a Glance:
* Pesticide Residues
The Bottom Line Data from recent industry financial reports. Dollar amounts in millions. Company Period Ended Sales BioTrove 1Q 31-Mar $2.0 BioTrove 2Q 30-Jun $2.6 ClemexTechnologies 4Q 30-Apr $1.3 ClemexTechnologies FYE 30-Apr $5.7 ClemexTechnologies 1Q 31-Jul $1.5 Fluidigm 6 Mo. 30-Jun $5.5 Galvanic Applied Sciences 4Q 30-Apr $3.1 Galvanic Applied Sciences FYE 30-Apr $13.0 Nanometrics 2Q 30-Jun $23.8 Pall 4Q 31-Jul $723.2 Pall (Medical) 4Q 31-Jul $131.8 Pall (BioPharmaceuticals) 4Q 31-Jul $131.3 Pall FYE 31-Jul $2,571.6 Pall (Medical) FYE 31-Jul $491.8 Pall (BioPharmaceuticals) FYE 31-Jul $483.4 RAE Systems 2Q 30-Jun $24.6 Robotic Tech. Sys. (Life Science) 6 Mo. 30-Jun $4.8 Smiths Group (Detection) FYE 31-Jul $1,018.6 Techne 4Q 30-Jun $67.8 Techne FYE 30-Jun $257.4 Techne (Biotechnology) FYE 30-Jun $165.7 Techne (R&D Europe) FYE 30-Jun $75.7 Zygo 4Q 30-Jun $48.5 Zygo FYE 30-Jun $159.0 Op. Company Chg. Prof. Chg. BioTrove 88.7% ($38.0) NM BioTrove 49.7% ($4.2) NM ClemexTechnologies 9.6% ($0.0) NM ClemexTechnologies 5.8% ($0.1) NM ClemexTechnologies 37.5% $0.1 NM Fluidigm 84.2% ($14.5) NM Galvanic Applied Sciences -31.9% ($1.5) NM Galvanic Applied Sciences -25.3% ($2.5) NM Nanometrics -36.4% ($19.0) NM Pall 11.9% $116.0 12.5% Pall (Medical) 1.1% N/A N/A Pall (BioPharmaceuticals) 13.3% N/A N/A Pall 14.3% $389.7 21.0% Pall (Medical) 3.5% N/A N/A Pall (BioPharmaceuticals) 19.4% N/A N/A RAE Systems 22.7% $0.5 NM Robotic Tech. Sys. (Life Science) -35.9% ($1.8) NM Smiths Group (Detection) 21.1% $170.0 35.8% Techne 16.0% $38.8 19.5% Techne 15.2% $144.3 16.2% Techne (Biotechnology) 13.0% N/A N/A Techne (R&D Europe) 22.6% N/A N/A Zygo 4.2% $2.3 -59.9% Zygo -12.1% $2.0 -90.8% Net Company Prof. Chg. BioTrove ($5.3) NM BioTrove ($5.9) NM ClemexTechnologies ($0.1) NM ClemexTechnologies ($0.2) NM ClemexTechnologies $0.1 NM Fluidigm ($15.3) NM Galvanic Applied Sciences ($1.0) NM Galvanic Applied Sciences ($1.8) NM Nanometrics ($18.9) NM Pall $69.9 316.7% Pall (Medical) N/A N/A Pall (BioPharmaceuticals) N/A N/A Pall $217.3 70.4% Pall (Medical) N/A N/A Pall (BioPharmaceuticals) N/A N/A RAE Systems ($0.5) NM Robotic Tech. Sys. (Life Science) N/A N/A Smiths Group (Detection) N/A N/A Techne $27.3 18.9% Techne $103.6 21.7% Techne (Biotechnology) N/A N/A Techne (R&D Europe) N/A N/A Zygo $1.1 -72.4% Zygo $1.2 -91.8% N/A = not available NM = not meaningful
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|Title Annotation:||gas chromatography-mass spectrometry|
|Comment:||Market profile: GC-MS in food analysis.(gas chromatography-mass spectrometry)|
|Publication:||Instrument Business Outlook|
|Article Type:||Statistical table|
|Date:||Sep 30, 2008|
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