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Many low-risk cancers get upgraded at prostatectomy.

FROM JOURNAL OF UROLOGY

Among prostate cancers judged to be low risk after physical exam and biopsy, 33%-45% were upgraded or upstaged at radical prostatectomy, a study has shown.

PSA density greater than 0.15 ng/ mL and the linear extent of cancer in mm within biopsy specimens were found to be highly predictive in this study of 4,500 cases of prostate cancers that were judged to be low risk before surgery, said Dr. Annelies Vellekoop of New York University, New York, and her associates. Three predictors of upstaging / upgrading--age over 60 years, high PSA level, and stage T2 cancer on biopsy--are already known to raise risk (J. Urol. 2014;191:350-7).

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Title Annotation:CANCER
Author:Moon, Mary Ann
Publication:Family Practice News
Date:Mar 1, 2014
Words:117
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