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Low carbohydrate vs. low fat diet.

Nutraceutical: Low Carbohydrate vs. Low Fat Diet

Indication; Weight Loss & Cardiovascular Risk Factors

Source: Annals of Internal Medicine 2014;161(5):309-318

Research: Low-carbohydrate diets are popular for weight loss, but their cardiovascular effects have not been well-studied, particularly in diverse populations. The aim of this study was to examine the effects of a low-carbohydrate diet compared with a low-fat diet on body weight and cardiovascular risk factors.

This randomized, parallel-group trial included 148 men and women without clinical cardiovascular disease and diabetes. Study subjects consumed a low-carbohydrate (<40 g/d) or low-fat (<30% of daily energy intake from total fat [<7% saturated fat]) diet. Both groups received dietary counseling at regular intervals throughout the trial. Data on weight, cardiovascular risk factors and dietary composition were collected at 0,3, 6 and 12 months.

Results: Sixty participants (82%) in the low-fat group and 59 (79%) in the low-carbohydrate group completed the intervention. At 12 months, participants on the low-carbohydrate diet had greater decreases in weight (mean difference in change, -3.5 kg [95% CI, -5.6 to -1.4 kg]; P = 0.002), fat mass (mean difference in change, -1.5% [CI, -2.6% to -0.4%]; P = 0.011), ratio of total-high-density lipoprotein (HDL) cholesterol (mean difference in change, -0.44 [CI, -0.71 to -0.16]; P = 0.002), and triglyceride level (mean difference in change, -0.16 mmol/L [-14.1 mg/ dL] [CI, -0.31 to -0.01 mmol/L [-27.4 to -0.8 mg/dL]]; P = 0.038) and greater increases in HDL cholesterol level (mean difference in change, 0.18 mmol/L [7.0 mg/dL] [CI, 0.08 to 0.28 mmol/L [3.0 to 11.0 mg/dL]]; P < 0.001) than those on the low-fat diet.

Researchers concluded the low-carbohydrate diet was more effective for weight loss and cardiovascular risk factor reduction than the low-fat diet. Restricting carbohydrates may be an option for people looking to lose weight and reduce cardiovascular risk factors.

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Title Annotation:Nutraceuticals Research
Publication:Nutraceuticals World
Date:Oct 1, 2014
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