Printer Friendly

Liver tumors and oral contraceptives.

Liver Tumors and Oral Contraceptives

A large survey of 477 hospitals was conducted to determine the number of primary benign and malignant tumors found in males and females between the ages of 15 and 45 years. The survey covered the years 1970 to 1975. The major objective was to determine whether women taking oral contraceptives were at greater risk for the development of liver tumors.

A total of 543 primary liver tumors were reported, with 378 occuring in females and 165 in males. Tumors were malignant in 91.5 percent of the males. In females, a higher percentage (56.1 percent) of benign tumors was found.

Sixty-five percent of the females with benign liver tumors had taken oral contraceptives. In women who did not use oral contraceptives, tumors were almost equally divided between benign and malignant.

The peak frequency of benign liver tumors occurred in patients 26 to 30 years of age, which would correspond to the time when oral contraceptives are most frequently used.

The most frequent benign tumors in users of oral contraceptives were hepatic cell adenomas and focal nodular hyperplasia. In nonusers, histologic types were almost equally divided among hepatic cell adenomas, focal nodular hyperplasia, hamartomas and other benign tumors.

These data suggest an association between oral contraceptives and liver tumors.
COPYRIGHT 1989 Vegetus Publications
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1989 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:Nutrition Health Review
Date:Mar 22, 1989
Previous Article:Alcohol link to breast cancer confirmed.
Next Article:Research links pill with breast cancer.

Related Articles
The "Pill's" dangers: should women be kept ignorant?
Cervical cancer rates higher among users of the pill.
Pill ups cancer risk in young women.
Use of any combined pill type confers an elevated risk of a first heart attack. (Digests).
Heaviest women have the most pill failures. (FYI).
No evidence OCs cause weight gain.
Oral contraceptives can be inhibited by antibiotics.

Terms of use | Copyright © 2016 Farlex, Inc. | Feedback | For webmasters