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Liquid chromatography--mass spectrometry, 3d ed.


Liquid chromatography--mass spectrometry, 3d ed.

Niessen, W.M.A.

CRC / Taylor & Francis


608 pages



Chromatographic science series; 97


The technology behind liquid chromatograpy and mass spectrography (LC-MS) has matured to the point where applications have become the focus of the most exciting research. Niessen (bio-pharmaceutical sciences, Free U., Amsterdam) continues to track the most recent literature for this edition, updating the technological basis for LC-MS and focusing on atmospheric-pressure ionization. He describes advances in small LC-MS molecule applications including the analysis of pesticides, environmental studies, drug discovery and development, drug metabolism, quantitative bioanalysis, clinical applications, and the analysis of steroids, food safety and plant phenols. He includes significant LC-MS biomolecule applications, including the analysis of proteins, peptides and enabling technologies, oligosaccharides, lipids and phospholipids, and nucleic acids, and applications in proteomics and the identification of post-translational modifications. In each case he shows how LC-MS works in the study, how to customize strategies and interpret results, and why the results are useful.

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Publication:SciTech Book News
Article Type:Book Review
Date:Dec 1, 2006
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