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LineaRx Anticipates Expansion in Diagnostics Market via Follow-on Order and New Linear DNA Amplicons for Additional Assay.

M2 PHARMA-May 22, 2019-LineaRx Anticipates Expansion in Diagnostics Market via Follow-on Order and New Linear DNA Amplicons for Additional Assay


- US-based LineaRx, a subsidiary of molecular technologies company Applied DNA Sciences, Inc. (NASDAQ: APDN), is in process of designing new, custom amplicons for an existing customer in the in vitrodiagnostics market, the company said.

This diagnostic assay is expected to be available and qualified in 2020, potentially resulting in increasing revenue from an existing supply agreement.

LineaRx currently receives annual orders for large-scale DNA from this customer under a five-year supply agreement executed in 2017.

The second annual purchase under the supply agreement was received earlier this year, and shipments will commence this quarter and continue for the following three quarters.

This purchase order yields revenue in excess of USD 500,000.

LineaRx believes linear DNA is ideal for diagnostic applications in that modifications to the target amplicon made through the PCR process are faster, more efficient and less costly than traditional chemical derivatization.

LineaRx seeks to commercialise the biotherapeutic value of Applied DNA's deep expertise and experience in the design, manufacture and chemical modification of DNA by large scale polymerase chain reaction.

Linear DNA is a form of DNA distinct from the circular form of DNA most commonly produced in plasmids and grown in bacteria. Plasmids are extrachromosomal DNA found in bacteria and are associated with the genes for antibiotic resistance which are often exchanged between bacteria and consequentially, are seen by many to embody a serious threat to global health.

In addition, many nucleic acid-based therapies also rely on viral vectors for efficient transfection and expression of plasmid DNA.

These viral vectors carry additional nontrivial risks and are extremely time consuming and expensive to manufacture.

Applied DNA is a provider of molecular technologies that enable supply chain security, anti-counterfeiting and anti-theft technology, product genotyping and pre-clinical nucleic acid-based therapeutic drug candidates.

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Publication:M2 Pharma
Date:May 22, 2019
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