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Left pulmonary artery thrombosis diagnosed by transesophageal echocardiography/Transozofajiyal ekokardiyografi ile tani konulan sol pulmoner arter trombozu.

A 65-year-old male patient was admitted with complaints of dyspnea and cough that has lasted for one week. On examination, the patient was tachypneic and cyanotic. His blood pressure was 130/80 mmHg, pulse rate was 120 beats/min, respiratory rate was 28/min. On cardiovascular examination, a grade 2/6 pansystolic murmur was heard at the left sternal border and right ventricular heave was palpable. His electrocardiogram showed an incomplete right bundle branch block and sinus tachycardia. The laboratory tests were normal except a mild leukocytosis. The arterial blood gases disclosed a Pa02 of 50 mmHg, a PaC02 of 38 mmHg and a pH of 7.45. The D-dimer level was <500 ng/ml. The transthoracic echocardiography revealed severe tricuspid regurgitation, mild mitral regurgitation, marked dilatation of the main pulmonary artery and the right ventricle. The systolic pulmonary artery pressure was 50 mmHg. The transesophageal echocardiography demonstrated an occlusion in the left pulmonary artery (Fig. 1, Video 1. See corresponding video/movie images at In the subsequent computed tomography (CT) angiography, the left pulmonary artery was found to be totally occluded (Fig. 2). Thromboembolism was no consistent with the CT angiography findings. The venous Doppler ultrasonography of the lower extremity and abdomen were normal. Screenings for connective tissue disease and thrombophilia were negative. It was decided to proceed with thromboendarterectomy, but he refused it. Upon this, heparin and warfarin were initiated and warfarin therapy was adjusted according to INR goal of between 2-3.


Pulmonary artery thrombosis is seen in Eisenmenger's syndrome, atrial septal defect and connective tissue diseases. However, none of these causes was in our case. The CT angiography and transesophageal echocardiography are being used in cases of pulmonary artery occlusion. Apart from treatment directed towards the causes, anticoagulants, fibrinolytics and surgical methods are being used.

It can be concluded that in patients with severe dyspnea together with the dilatation of the right heart chambers on transthoracic echocardiography, further investigation of the main pulmonary artery together with proximal left and right pulmonary arteries should be evaluated with transesophageal echocardiography.


Note: This case was presented at National Echocardiography Meeting, 4-6 May 2006, Konya, Turkey

Hamza Duygu, Filiz Ozerkan, Mustafa Akin

Department of Cardiology, Faculty of Medicine, Ege University, Izmir, Turkey

Address for Correspondence/Yazisma Adresi: Hamza Duygu, MD 4834 sokak, No: 20, Kat: 2, Yenicamlik, 35400, Izmir-Turkey Phone: +90 232 390 40 01 Fax: +90 232 390 32 87 E-mail:
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Title Annotation:E-page Original Images/E-sayfa Orijinal Goruntuler
Author:Duygu, Hamza; Ozerkan, Filiz; Akin, Mustafa
Publication:The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi)
Geographic Code:7TURK
Date:Apr 1, 2008
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