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LEDERLE REBATING ONE-THIRD THE COST OF PROSTEP(R) NICOTINE PATCH THERAPY, AND DONATING 1 MILLION MORE PATCHES TO ASTHO

 -- Rebate Program Will Reduce Patch Price to That of Cigarette Pack;
 Company Making Pro-Step More Accessible To Eligible Smokers After
 Tremendous Public Response to Initial ASTHO Donation --
 WAYNE, N.J., March 4 /PRNewswire/ -- Lederle Laboratories, responding to the phenomenal positive public reaction (including tens of thousands of phone calls) to the February 23 announcement that Lederle is donating two million ProStep(R) nicotine patches free of charge to the Association of State and Territorial Health Officials (ASTHO), today announced the following two unprecedented corporate initiatives to help adults quit smoking: (Please see warnings and contraindications at end of press release.)
 -- Lederle is rebating the cost of ProStep(R) nicotine transdermal system therapy by approximately one-third to make ProStep more readily accessible to eligible smokers who want to quit but aren't able to access free ProStep through the ASTHO donation to health departments. This extraordinary rebate to eligible smokers reduces the average price of each ProStep nicotine patch -- $4.00 -- to the average price of a pack of branded cigarettes -- $2.50.
 -- Lederle will donate an additional one million ProStep nicotine patches to ASTHO for distribution, free of charge, to state health departments for use in state, county and local health departments and other community smoking cessation programs across the country.
 ProStep, available by a doctor's prescription only, is an aid to smoking cessation for the relief of nicotine withdrawal symptoms. ProStep should be used as part of a comprehensive behavioral smoking cessation program.
 Effective immediately, Lederle will rebate to any eligible patient who begins ProStep therapy between March 1, 1993 and June 30, 1993, and completes a minimum of six continuous weeks of therapy, $1.50 a day, making the cost of a ProStep nicotine patch equal to the average cost of a pack of branded cigarettes. This rebate results in a $63.00 savings on a six week course of therapy. Eligible patients must save their box tops and register receipts from a minimum of six continuous weeks of ProStep therapy, and mail these materials along with their name, address and phone number, printed legibly, to ProStep Rebate, P.O. Box 15921, Cincinnati, Ohio, 45215-9998. Interested consumers can call, free of charge, 1-800-678-7837 and interested physicians and pharmacists can call 1-800-551-7837. After calling the toll-free number, consumers will receive written information on the ProStep Rebate Program. The rebate should be mailed directly to the patient within four to six weeks.
 ProStep rebates are not available for prescriptions reimbursed under Medicaid, similar federal or state programs, other private reimbursement programs or where prohibited by law.
 Lederle is taking these actions in response to ASTHO's request for support of greater public health efforts in the area of smoking cessation. An overwhelming and tremendously positive public response greeted the February 23 announcement that Lederle was donating two million ProStep patches to ASTHO, to be provided to state health departments for distribution to state, county and local health departments, as well as other community smoking cessation programs throughout the U.S.
 "Phones were ringing off the hook at Lederle, at ASTHO, and at state, county and local health departments around the country," said Edward V. Fritzky, President of Lederle. "We are delighted that so many American smokers really want to quit and are so interested in using ProStep as an aid to their efforts. We are donating one million more patches and cutting the cost of ProStep therapy by approximately one- third through a rebate program that will give eligible adult smokers in the U.S. the incentive to kick their habit, for the sake of their own health and that of their families, friends and co-workers."
 "Lederle's initial ProStep donation to ASTHO turned a new page in the history of public-private partnerships to improve the health of American families," said M. Joycelyn Elders, M.D., President of ASTHO, Director of the Arkansas Department of Health and U.S. Surgeon General- designate. "By increasing their donation of ProStep to ASTHO and sponsoring a nationwide program that enables smokers to trade the cost of their nicotine addiction for the cost of potentially beating that addiction, Lederle is writing a brand new chapter on our country's health."
 "Lederle Laboratories' initiative takes a major step towards meeting the President's agenda to reduce health care costs," said U.S. Senator Frank Lautenberg (D-NJ), the leading Congressional proponent of anti- smoking legislation. "Not only is Lederle making an important smoking cessation aid greatly accessible to the population, but the smokers who quit as a result of this program will contribute to reduced health care costs associated with the treatment of smoking-related diseases."
 "I strongly support the anti-smoking efforts currently being made by Lederle," said U.S. Senator Bill Bradley (D-NJ), who yesterday announced a proposal to raise the federal excise tax on tobacco. "In addition to the health risks, smoking related diseases add $50 billion in health care costs to our economy annually. Health care reform means reforming our health and Lederle is leading the way in helping people overcome their addiction to tobacco."
 ASTHO will distribute the three million free ProStep patches to state health departments for use in state, county and local health departments and other community smoking cessation programs across the country. The public-private partnership between Lederle and ASTHO will supply enough ProStep to treat approximately 75,000 smokers with the recommended course of ProStep therapy.
 In addition to providing free ProStep therapy, Lederle will also make available to smokers who participate in the ASTHO program adjunctive patient support services, such as the ProStep Bilingual Support Hotline, which provides live, one-on-one advice, encouragement and motivation by trained smoking cessation specialists, and the ProStep Referral Service, which provides referrals to local smoking cessation programs via a separate toll free hotline.
 ASTHO is now working with state public health offices to determine the quantity of ProStep therapy that will be allocated to each state and to finalize plans for using ProStep as part of smoking cessation programs in all the states that are receiving the donation.
 ASTHO encourages smokers who are interested in participating in the ProStep donation program to watch and listen to their local media in upcoming weeks for information from their state public health departments about the specific timing and nature of the ASTHO community smoking cessation program in their area. Interested smokers can call 1-800-645-7837 for information.
 Lederle's donation of three million ProStep nicotine patches to ASTHO, as well as the ProStep Rebate Program, are extensions of its ongoing commitment to smoking cessation. These actions are also a response to last month's Environmental Protection Agency (EPA) report classifying second hand tobacco smoke as a human carcinogen, as well as several other recent studies citing new evidence that smoking and passive smoke pose health risks not only to smokers, but also their spouses, friends, co-workers and their children. Additionally, these programs fulfill ASTHO's request for greater private industry support of public health efforts.
 The Association of States and territorial Health Officials is a national membership organization whose purpose is to formulate and influence, through collective action, the establishment of sound national public health policy and to assist and serve state health departments in the development and implementation of state programs and policies. The Tobacco Use Prevention and Control Program is carried out by a network of contacts in each state department to promote clean indoor air policies, reduce youth access to tobacco products, and foster smoking cessation programs.
 Lederle Laboratories, a division of American Cyanamid Company (NYSE: ACY), is a research-intensive organization that manufactures and markets worldwide a broad range of healthcare products, including ethical pharmaceuticals, generics, vitamins and nutritionals.
 NOTES: Please consult full prescribing information for ProStep.
 Patients should not smoke or use other nicotine-containing products during ProStep treatment. ProStep should not be used continuously for longer than three months. The effects of ProStep on fetal development are unknown. Therefore, pregnant or nursing smokers should be encouraged to attempt smoking cessation using educational and behavioral interventions before using pharmacological approaches. The benefits of nicotine replacement in cardiovascular or peripheral vascular disease should be carefully weighed against the risks. Since patients on concomitant medication may need dosage adjustment, it is important to ask patients if they are taking any other medications.
 -0- 3/4/93
 /NOTE TO EDITORS: Please include the toll free phone numbers in all your coverage to better instruct interested consumers on obtaining further information about these programs.
 For background on ASTHO or Lederle, fact sheets on the EPA Report on Environmental Tobacco Smoke, new studies on the effects of smoking or cigarette smoking in the workplace, please call Steve Hull, MCS, 908-273-9626/
 /CONTACT: Pat Fiaschetti, 201-831-4684, or Jeff Hoyak, 201-831-4619, both of Lederle Laboratories/
 (ACY)


CO: Lederle Laboratories ST: New Jersey IN: MTC SU:

TM-LD -- NY006 -- 2913 03/04/93 11:01 EST
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