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LEADING SCIENTISTS SAY HAIR DYE STUDY WRONG, NEEDLESSLY ALARMIST

LEADING SCIENTISTS SAY HAIR DYE STUDY WRONG, NEEDLESSLY ALARMIST
 WASHINGTON, July 1 /PRNewswire/ -- The Cosmetic, Toiletry, and Fragrance Association issued the following:
 The Sheila Zahm study on hair dye safety is incorrect and needlessly alarmist, say a number of the nation's leading epidemiologists and public health academicians, responding to an article in the July issue of the American Journal of Public Health. They conclude that the research reported in the Journal is questionable in its interpretations and erroneous in its conclusions.
 According to the U.S. Food and Drug Administration, in a statement released Tuesday, "the study's design does not allow the establishment of a causal link between hair dye and increased cancer." FDA and the National Cancer Institute both agree that "no recommendation to change patterns of hair dye use can be made at this time, based on these research results."
 After a methodological evaluation of the study, Alvan Feinstein, M.D., Sterling professor of medicine and epidemiology at Yale University School of Medicine, concluded "the work has so many scientific defects that it cannot be regarded as credible."
 Concurring with this conclusion, Dr. Burton Singer, professor of epidemiology and public health at Yale, commented, "The very provocative and suggestive conclusions in the paper ... are simply not warranted by the data presented in the tables."
 The safety and effectiveness of hair coloring products have been tested thoroughly over the many years of their use. Independent research by numerous scientific institutions, including Harvard, Yale and Oxford, has shown no significant differences in cancer rates between users and non-users of hair dyes.
 Over the last decade, the cancer-causing potential of hair dyes was evaluated also by the U.S. Food and Drug Administration, the International Commission for Protection Against Environmental Mutagens and Carcinogens and the International Agency for Research on Cancer. None of these reviews found any evidence to support the hypothesis that hair dye poses a cancer risk. Their conclusions support the results of a previous Harvard study which also failed to find a cause-and-effect relationship between hair dye use and cancer.
 The Journal reports on a study that was originally designed to assess correlation between pesticide exposure and cancer, particularly non-Hodgkin's lymphoma, in farmers in eastern Nebraska. This is important, as the incidence of this type of lymphoma is higher among flour processing and agricultural workers. Further, in many cases, the research involved next-of-king interview, asking survivors of non-Hodgkin's lymphoma victims to recall the personal care habits of their long-deceased relatives. Additionally, several of the tables provide data that run counter to the conclusions in the paper. These include subjects who experienced higher exposure to hair dyes, yet had a lower incidence of lymphomas.
 "In summary, the inconsistencies in these data raised a question mark about the authors' interpretations of them as being positive," said Dr. Roy Shore, professor of epidemiology and biostatistics at New York University. "Their failure to do the most appropriate analyses (of exposure) is an egregious omission."
 The Cosmetic, Toiletry, and Fragrance Association is confident in the safety of hair dyes, understands the concerns that can be raised by this type of questionable data and encourages hair dye users not to be alarmed. These products have been used for many years and have a strong safety record supported by the existing body of extensive scientific and medical research.
 To answer consumer questions on this matter, CTFA has established a toll-free telephone line -- 800-824-1312.
 Citations:
 Harvard
 Hennekens CH et al., Use of permanent hair dyes and cancer among
 registered nurses. The Lancet, June 30, 1979, P. 1390.
 Yale
 Teta J., Walrath J., Meigs W., and Flannery J., Cancer incidence
 among cosmetologists. J. Natl. Cancer Inst. 72, 1051, 1984.
 Oxford
 Kinlen, L.J. et al., "Hair Dyes - Epidemiological evidence.
 Symposium on the interpretation of negative epidemiological
 evidence for carcinogenicity." 1983 Symposium at Oxford, IARC
 Publ. 65, 1985, pp. 57-68.
 Other Reviews
 ICPEMC Mutation Research 87, 1981, 63-79.
 IARC, Monograph Volume 27, pp. 307-318 (by Clemmesen).
 FDA Federal Register, Vol. 44, Oct. 16, 1979, P. 59522
 -0- 7/1/92
 /CONTACT: Irene Malbin, 202-331-1770, or Laura Armstrong, 202-835-8830, both for the Cosmetic, Toiletry, and Fragrance Association/ CO: Cosmetic, Toiletry, and Fragrance Association ST: District of Columbia IN: HEA SU:


TW -- DC028 -- 5856 07/01/92 16:03 EDT
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Date:Jul 1, 1992
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