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L-carnitine L-tartrate (LCLT). (Raw Material Research).

Raw Material: L-carnitine L-tartrate (LCLT)

Indication: Exercise recovery

Source: Am J Physiol Endocrinol Metab 2002, Feb;282(2):E474 -82

Research: With the use of a balanced, crossover design (1 week washout), 10 resistance-trained men consumed a placebo or LCLT supplement (2 g L-carnitine/day) for three weeks before obtaining blood samples on six consecutive days (D1 to D6). Blood was also sampled before and after a squat protocol (5 sets, 15-20 repetitions) on day two. Muscle tissue disruption at mid thigh was assessed using magnetic resonance imaging (MRI) before exercise and on day three and six.

Results: Exercise-induced increases in plasma markers of purine catabolism (hypoxanthine, xanthine oxidase and serum uric acid) and circulating cytosolic proteins (myoglobin, fatty acid-binding protein, and creatine kinase) were significantly attenuated by LCLT. Exercise-induced increases in plasma malondialdehyde returned to resting values sooner during LCLT supplementation compared with placebo. The amount of muscle disruption from ME1 scans during LCLT was 4145% of the placebo area. These data indicate that LCLT supplementation is effective in assisting recovery from high repetition squat exercise.
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Publication:Nutraceuticals World
Article Type:Brief Article
Geographic Code:1USA
Date:Sep 1, 2002
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