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Keys to successful gout management.

"Gout is the most common inflammatory arthritis in the world. Over the last several decades the prevalence and incidence of gout has risen in both sexes. Gout is associated with hypertension, metabolic syndrome, and renal disease, and may turn out to be an independent risk factor for cardiovascular disease as supporting evidence continues to accumulate. Despite the antiquity of gout and our knowledge of the underlying pathophysiology, there remain many misperceptions of what gout is and how it can impact patients' overall health, morbidity and mortality. The keys to successfully managing gout, both short and long term, indude patient education, shared decision-making, reducing to and maintaining a serum urate level below a defined target (i.e., below 6 mg/dL given that the limit of solubility of uric add is 6.8 mg/dL), and long-term adherence to urate-lowering therapy in order to maintain the target serum urate. Despite the absence of clinical trials evaluating a therapeutic target in gout, there is insurmountable evidence that by 'treating to target' patients can eventually be 'cured' of gout and its associated maladies."

ROBERT T. KEENAN, MD, MPH Rheumatologist, Duke

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Title Annotation:THE VIEW FROM DUKE
Author:Keenan, Robert T.
Publication:Duke Medicine Health News
Date:Jan 1, 2017
Previous Article:New strategy for gout: Treat-to-Target goals: unlike other rheumatic diseases; clear, therapeutic targets for gout--a potentially curable...
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