U.S. Patent 8,187,708 (May 29, 2012), "Microphasic Micro-Components and Methods for Controlling Morphology via Electrified Jetting," Joerg Lahann and Abbass Kazemi (University of Michigan, Ann Arbor, Michigan, USA).
Tiny particles, with diameters between nanometers and millimeters, can be useful in drug delivery, sensors, micro-reactors, imaging, and food packaging, but conventional production methods are expensive and time-intensive. Lahann and Kazemi have prepared multiphase nano- to micro-particles such as core-shell or anisotropic (Janus) multiphase particles with well-defined structures using electrohydrodynamic co-jetting of two different polyelectrolyte solutions. In this process, the two streams break up into droplets, forming the particles during jetting. Candidate polyelectrolytes include polyacrylic acid, poly(acrylamide acrylic acid), poly(acryl amide-co-acrylic acid), sodium polystyrene sulfonate, polyethylene imine, polypeptides, and copolymers. The relative conductivities of the two jetting solutions determine particle morphologies After crosslinking, the core-shell particles are stable in aqueous suspensions with reproducible swelling while maintaining the original coreshell structure. In addition, these nanoparticles are pH-responsive, important for delivery of nano-drugs and micro-drugs.
Roger D. Corneliussen is Professor Emeritus of Materials Engineering, Drexel University, in Philadelphia, Pennsylvania, USA. He is editor of Maro Polymer Alerts and the Maro Polymer website (www.maropolymeronline.com). He has been active in SPE since 1962 and has served on the Board of the Philadelphia Section and as SPE Councilor. For Maro Patent Alerts, he reviews all U.S. Patents weekly, makes links to the polymer-related patents, and sends the links daily to subscribers. These patent abstracts are based on the weekly selection process. To sample Maro Patent Alerts, email a request to email@example.com.
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|Title Annotation:||INDUSTRY PATENTS|
|Article Type:||Brief article|
|Date:||Sep 1, 2012|
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