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Japanese researchers generate pancreatic islet with iPS cells.

TOKYO, March 17 Kyodo

A team of Japanese researchers has succeeded in generating a pancreatic islet for controlling blood sugar levels using induced pluripotent stem cells, known as iPS cells, they said Sunday.

The team of Atsushi Miyajima, a professor at the Institute of Molecular and Cellular Biosciences at the University of Tokyo, and Ami Watanabe, a researcher at the institute, confirmed that the pancreatic islet functioned properly and lowered blood sugar levels to normal once transplanted into a mouse with a type of diabetes.

Their findings will be presented to the Japanese Society for Regenerative Medicine on Friday, they said.

The team now intends to develop methods for the mass generation of pancreatic islets at lower cost for the treatment of diabetes through transplantation, while working towards shortening the one-month period currently required for creating pancreatic islets.

The team earlier succeeded in generating a three dimensional conformation that is unique to pancreatic islets, but it required a longer time to create and the conformation could not produce sufficient insulin.
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Publication:Japan Science Scan
Date:Mar 18, 2013
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