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Isoflavones flunk out.

Soy isoflavones (including genistein and daidzein) failed to prevent bone loss or hot flashes in one of the biggest studies done so far.

Researchers assigned 182 women (all had been menopausal for no more than rive years) to take either 200 milligrams of a soy isoflavone tablet or a placebo every day. Women who consumed less than 1,000 mg of calcium a day were also given calcium and vitamin D supplements.

After two years, those who took the isoflavones had no higher spine or hip bone density than those who took the placebo. Surprisingly, more soy isoflavone takers (48 percent) than placebo takers (32 percent) reported hot flashes.

What to do: Don't expect soy isoflavone supplements to prevent hot flashes or bone loss. And so far, there isn't enough evidence to say that soy foods protect bones or prevent hot flashes either.

Arch. Intern. Med. 171:1363, 2011.

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Title Annotation:QUICK STUDIES
Publication:Nutrition Action Healthletter
Article Type:Brief article
Geographic Code:1USA
Date:Oct 1, 2011
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