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Investigations of capricious gene expression in drosophila wing development. (Senior Division).

The purpose of these experiments was to determine the relationships among a group of mutants of the fruit fly Drosophila melanogaster in a visible deletion associated with the Lyra wing phenotype, as well as the function of the gene, capricious, in wing development. The mutants are known to form two lethal complementation groups: senseless (sens) (Nolo et al, 2000) and capricious (caps). Complementation crosses, deletion mapping, gene expression, and sequence analyses were used to investigate the mutants of the caps group, locate them on the third Drosophila chromosome, and determine their function in wing development. Three mutants: E70 (chemically induced), 1(3)02937 (a LacZ insertion mutant), and caps 65.2 (an excision mutant), all appear to be in or near the caps coding region. Three other LacZ insertion mutants: p1052, 1(3)02937, and caps E2-3- 27, have the same expression patterns in wing discs. This suggests that they are regulatory mutants, and the position of the p1052 insertion upstream of the coding region is consistent with this conclusion. Because several of the mutants show expression in

Michelle S. Itano Fairview High School, Boulder, CO.
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Author:Itano, Michelle S.
Publication:Journal of the Colorado-Wyoming Academy of Science
Article Type:Brief Article
Geographic Code:1USA
Date:Apr 1, 2002
Words:186
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