Intraoral Shwannoma mimicking mucocele: a case report.
CASE HISTORY: A thirteen year old boy presented with a swelling on the undersurface of the tongue. Examination revealed 1 x 1 cm swelling with smooth external surface which was cystic in consistency.
Excision biopsy of the lesion revealed 1.7 x 1 x 0.8cm encapsulated mass with smooth surface and glistening brown, soft to firm cut-surface.
Microscopy showed an encapsulated tumour covered by a stratified squamous epithelium and skeletal muscle, composed of interlacing fascicles of spindle shaped cells with elongated wavy nuclei, moderate amount of eosinophilic cytoplasm and indistinct cell borders. Numerous Verocay bodies were present. On immunohistochemistry, the cells were strongly positive for S-100.
DISCUSSION: Schwannomas are the most common benign nerve sheath tumours that arise from Schwann cells. Though they can occur at any site, they are more commonly seen in the head and neck region and in the extremities where they arise from small to medium sized nerves. One third of the extracranial schwannomas occur in the head and neck region and 1% of the head and neck schwannomas occur in the oral cavity. (6,7,8) In the oral cavity, the tongue is the most common preferred site followed by the palate and buccal mucosa. (3,6,9) They are usually solitary, encapsulated tumours composed of cellular Antoni A areas, hypocellular Antoni B areas and Verocay bodies where rows of nuclei line up in a nuclear palisade. In our case the lesion was composed mainly of Verocay bodies.
Schwannomas occur in all age groups and are mostly seen in people between second to fifth decade. Intra oral schwannomas have been described in people between second to third decade. (10)
Given that intra oral schwannomas are a very rare occurrence, it is quite often misdiagnosed as a mucocele, ranula, traumatic fibroma or a fibroepithelial polyp. Our case presented as an intraoral swelling with cystic consistency and was clinically diagnosed as a mucocele.
Histopathology followed by immunohistochemistry confirmed the diagnosis of schwannoma.
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Shobha H. B , Anusha Kumari , Sowmya S. V 
[1.] Shobha H. B.
[2.] Anusha Kumari
[3.] Sowmya S. V.
PARTICULARS OF CONTRIBUTORS:
[1.] Final Year Post Graduate Student, Department of General Pathology, Christian Medical College, Vellore.
[2.] Assistant Professor, Department of General Pathology, Christian Medical College, Vellore.
[3.] Assistant Professor, Department of Dental Sciences, Christian Medical College, Vellore.
NAME ADDRESS EMAIL ID OF THE CORRESPONDING AUTHOR:
Dr. Shobha H. B, 3rd F Cross, 3rd Stage, 2nd Block, 4th Main, Basaveshwara Nagar, Bangalore-79.
Date of Submission: 02/09/2014.
Date of Peer Review: 14/10/2014.
Date of Acceptance: 23/12/2014.
Date of Publishing: 01/01/2015.
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|Title Annotation:||CASE REPORT|
|Author:||Shobha, H.B.; Kumari, Anusha; Sowmya, S.V.|
|Publication:||Journal of Evolution of Medical and Dental Sciences|
|Date:||Jan 1, 2015|
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