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Innate Pharma SA concludes target enrollment of 150 Acute Myeloid Leukemia patients in EffiKIR trial.

M2 EQUITYBITES-July 25, 2014-Innate Pharma SA concludes target enrollment of 150 Acute Myeloid Leukemia patients in EffiKIR trial


Biopharmaceutical company Innate Pharma SA (Euronext Paris: FR0010331421) revealed on Thursday that it has completed target enrollment in the EffiKIR trial with 150 Acute Myeloid Leukemia (AML) patients randomised.

The company added EffiKIR is a double-blind placebo-controlled randomized Phase II trial of lirilumab as maintenance treatment in elderly patients with Acute Myeloid Leukemia (AML) in first complete remission. The primary efficacy endpoint is leukemia-free survival. Secondary endpoints include safety and overall survival.

This trial is based on the capacity of activated Natural Killer (NK) cells to directly kill tumor cells and trigger broad immune activation. The clinical studies show that activated NK cells can significantly lower the recurrence of various hematological malignancies, including AML, following hematopoietic stem cell transplantation, said the company.

According to the company, the trial is sponsored by Innate Pharma within the context of the licencing agreement with Bristol-Myers Squibb Company (NYSE:BMY) and is performed in France, with the participation of the two French clinical cooperative groups, ALFA and GOELAMS.

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Publication:M2 EquityBites (EQB)
Date:Jul 25, 2014
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