The first intravenous formulation of ibuprofen, Caldolor, has been
approved to treat pain and fever and is available for in-hospital use
only. The approved dosages for Caldolor are 400-800 mg IV over 30
minutes, every 6 hours for acute pain; and 400 mg over 30 minutes,
followed by 400 mg every 4-6 hours, or 100-200 mg every 4 hours, as
needed, for fever. Caldolor should be used with caution in the elderly,
in patients with a prior history of ulcer disease or GI bleeding, in
those with fluid retention or heart failure, in those with renal or
liver impairment, and in those taking diuretics or ACE inhibitors.
Cumberland Pharmaceuticals Inc.