Printer Friendly

Influence of some vegetable extracts from Uzbekistan's flora on blood lipid spectrum of under experimental endogenous and ethanol hyperlipidemia.

Introduction

Flora (1) represents a rich opportunity for developing highly active preparations, including those for treatment of cardiovascular diseases. In territory of the former Soviet Union 20 thousand species of medical plants grow. About 30% of known plants in the CIS grows in Uzbekistan. Many of them are widely used in cardiology practice for the prevention and treatment of atherosclerosis, myocardial infarction, as antiarrhythmic agents.

High morbidity and mortality from atherosclerosis makes one of the most significant the policy of the disease effective prevention and pharmacotherapy (Akopov, 1990). Meanwhile modern antiatherosclerotic (mainly lipid-lowering) drugs are likely to provoke a number of side effects and complications, even stimulation of carcinogenesis (Aripov and Fesenko, 2000). Taking into account the necessity of durational appliance of this type of drugs it was considered reasonable to conduct the search of hyperlipidemic agents among the plants, since they are close to the organism of mammals in terms of evolution and that is why they are well tolerated by the patients on durational appliance (Devidenkova and Shafran, 1998).

Materials and methods

The experiments were performed on 659 white mongrel male rats. During the series of the experiments which lasted five days, Plant extracts were administered per os at a dose of 10 mg/kg. On the 6th day hyperlipidemia (endogenous) was provoked by fasting animals for 24hours without limiting consumption of water (Mesherskaya and Sonina, 1972). Ethanol hyperlipidemia was induced by injecting 50% ethanol per os in doses: on the first day of the experiment 2g/kg, on the second day--4g/kg, on the third day--6g/kg body weight (Leontiva and Rijenkov, 1979).

Animals which were under etheric narcosis were slaughtered by decapitation. The research was conducted on the blood serum and erythrocytic mass. The concentrations of overall cholesterol (OChS), triglycerides (TG), cholesterol high-density lipoprotein (ChS HDL) were assessed by enzymatic method on auto analyzer "Daytona" (Randon, UK); the content of overall lipid (OL)--via the colorimetric method using panel "Lechama" (Czech Republic); the concentration of ceruloplasmin (CP) was found by the Ravin method, the rate of peroxide haemolysis erythrocyte (PHE) was defined as well.

Statistical processing of numerical data was conducted by standard methods of variation statistics using Student's t-test for assessing reliability of differences in Excel-2000 program. Mean values were represented as M [+ or -] m (mean [+ or -] average error of the mean).

Results of research

The research revealed the range of considerable changes in lipidic spectrum of blood of animals on experimental endogenous hyperlipids (Table 1). The obtained data prove that under the endogenous hyperlipidemia the level of OChS and TG in blood serum makes up to 1.84 [+ or -] 0.15 mmol/l and 1.03 [+ or -] 0.05 mmol/l, respectively, that on 71.9 and 43,1% higher in comparison with such indices of intact animals (1.07 [+ or -] 0.03 mmol/l and 0.73 [+ or -] 0.041 mmol/l).

On the contrary, the content of ChS HDL decreased to 21.7% and composed 0.47 [+ or -] 0.033 mmol/l opposite to 0.6 [+ or -] 0.036 mmol/l in norm. Endogenous hyperlipidemia resulted in increasing the rate of OL in blood serum by 52.0% which made up to 6.61 [+ or -] 0.26 g/l, in intact animal group analogous accounted for 4.35 [+ or -] 0.17 g/l.

The great number of works focusing on lipids peroxidation (LPO) processes in aetiology and pathogenesis of atherosclerosis has emerged recently. It is well known that control of LPO in organism processes is accomplished by antioxidative systems (AOS) (Vidal, 2002; Tertov, 1999). CP is considered to be the most important antioxidant in blood serum. This made reasonable to study the effect which the extract delivers on the level of serum in the blood. The findings showed that under experimental endogenous hyperlipidemia the content of CP in blood serum drops 1.2 times in comparison with the indices of intact animal group (Table 2). Thus, level of blood serum of intact animals and controlled group accounted for 16.82 [+ or -] 2.24 ml/dl and 13.08 [+ or -] 1.38 ml/dl, respectively. Decrease in the level of antioxidants including CP can lead to increase of auto-oxidation of lipidic membrane erythrocyte, which reduces the resistance to haemolysis. In connection with this, we studied PHE in erythrocytic mass. Under endogenous hyperlipidemia the tendency to increase for PHE was observed: in the intact group given index made up 13.87 [+ or -] 0.66 %, and in controlled - 16.18 [+ or -] 0.12%.

Initial screening in the vegetable extracts found that the most expressed hyperlipidemic and antioxidative effect were observed in the following extracts: leaves of Juniperus turkestanica Kom, aboveground part of Acantholimon erythraeum Bge, fruit of Descurania Sophia (L) Schur, aboveground part of Trigonella pamirica Boriss, seeds of Avena sativa, roots of Phlomis olgae Rgl. When injecting the extracts from Juniperus turkestanica Kom, the decrease was observed in concentration of OChS and TG in blood serum by 45.7 and 30.1% in comparison with the control value of this parameter. With this process the content ChS HDL increased by 19.1%. Under influence on this extract the drop of OL for 1.4 times was observed and the increase in content of CP for 15%. Extract from the leaves of Juniperus turkestanica Kom practically did not affect on the level of PHE.

Extract which was elicited from the aboveground part of Acantholimon erythraeum Bge was similar to Juniperus turkestanica Kom in terms of the influence. Vegetable extract, which was extracted from fruit of Descurania Sophia (L) Schur and overground part of Trigonella pamirica Boriss, decreased the concentration of OChS by 46.7 and 45.7%; TG in blood serum - by 29.1 and 28,2% in comparison with the control group, respectively. In the meantime, the content of ChS HDL increased by 12.8% and 14.9% respectively. Under influence of above mentioned extracts there was a decrease in OL in blood by 33.6 and 31.3%, and the increase in content of CP by 1.2 and 1.6 times in comparison with controlled values, respectively. The level of PHE was not changed under influence of these extracts.

Extracts of Avena sativa seeds and roots of Phlomis olgae Rgl supported significant decrease in OL, OChS, TG, as well as increase in content of Ch HDL and CP in blood serum of experimental animals. The changes in PHE were statistically insignificant.

No other extracts either revealed hyperlipidemic, antioxidational and membrane stabilizer effects or showed sufficient effectiveness, or were effective in all the studied parameters. Primary screening of the 106 extracts for presence of hyperlipidemic, antioxidational and membrane stabilizer effects under ethanol hyperlipidemia showed that on given models of hyperlipidemia there are also changes in lipidic blood spectrum (Table 3). Ethanol hyperlipidemia brings to the increase in OChS and TG by 75.6 and 72.1%, respectively in comparison with indices of the intact animals group. The content of ChS HDL reduced by 39.1% and made up 0.28 [+ or -] 0.04 mmol/l, in contrast to 0.46 [+ or -] 0.9 mol/l in norm. The given model led to the increase in OL concentration in the blood serum by 49.6%, which accounted for 6.3 [+ or -] 0.43 g/l, whereas the indices of intact animal analogues came up to 4.21 [+ or -] 0.36 g/l.

Ethanol hyperlipidemia brought to the decrease in the content of CP by 35.6% in comparison with normal indices. Thus, the level of CP in blood serum in intact animal and controlled group accounted for 16 [+ or -] 0.66 and 10.3 [+ or -] 0.9 mg/dl, respectively. Under ethanol hyperlipidemia there was insignificant rise in PHE: in the group of intact animal indices running up to 11.3 [+ or -] 0.8%, and in the control group--17.1 [+ or -] 0.8%.

The conducting primary screening on model of ethanol hyperlipidemia showed that not all previously educed active extracts under endogenous hyperlipidemia possess identical hyperlipidemic quality. Thus, the extract of Juniperus turkestanica Kom leaves had a strong hyperlipidemic effect on endogenous hyperlipidemia, whilst on ethanol hyperlipidemia there was a tendency to decrease in OChS, TG and OL; practically there was not effect on ChS HDL. Under the influence of this particular extract the increase in CP level by 54.5% was observed as well as an insignificant decrease of PHE in comparison with the control (Table 4). The extracts which were taken from overground part of Acantholimon erythraeum Bge, fruit of Descurania Sophia (L) Schur practically did not effect on the spectrum of blood. However, when injecting these extracts to animals there was significant rise in CP in blood but no effect on PHE. Extract from aboveground part of Trigonella pamirica Boriss had weak hypolipidic effect under ethanol hyperlipidemia. So, the decrease in OChS, TG and OL content was statistically insignificant under influence of this extract.

From all the previously revealed active extracts, the seeds of Avena sativa had the most marked hypolipidic, antioxidative and membrane stabilizer qualities. Researches of this extract showed that under its influence the lipidic spectrum of the blood normalizes the indices of antioxidant system and PHE improves. From the results of initial screening of vegetable extracts in two models of hyperlipidemia, the most perspective extract Avena sativa was chosen for further examination for its hypolipidic and antiatherosclerotic features.

References

Akopov, I., 1990. Important domestic herbal medicine and their application [Vazhnejshie otechestvennie lekarstvennie rasteniya i ih primenenie], in Russian, Tashkent: Medicine..

Aripov, A., Fesenko, L., 2000. Clinical Biochemistry. Methods [Kilicheskay biohimia. Metodi], in Russian, Medical Literature Publishing House named after Abu Ali ibn Sino, Uzbekistan, Tashkent.

Devidenkova, E., Shafran, M., 1998. "Atherosclerosis and lipid peroxidation process," Bulletin AMN USSR [Vestnik AMN SSSR], in Russian, No.3, pp.10-13.

Nasirov, Sh., Sobirov, D., 2005. "Ischemic heart disease (pathogeny, diagnostics it treatment): Science and technology", Republic of Uzbekistan, Tashkent.

Vidal, 2002. Medical products in Russia. Reference Book, 8th edition, Russian Federation, Moscow: Astra Farm Service.

Tertov, V., 1999. "Multiple-modified low-density lipoproteids, circulation in human's blood", Angiology and vascular surgery, No5 (suppl.), pp. 218-239.

[1] ADOLAT ZIYAEVA, [2] NOSIR YULDASHEV

[1] Republican Specialized Centre of Cardiology, [2] Tashkent Pediatric Medical Institute, Uzbekistan

(1) The study has been supported by grant No.A-10-035 'Search and development of new medical products from the flora of the Republic of Uzbekistan for prophylaxis and treatment of atherosclerosis'.
TABLE 1. SCREENING OF VEGETABLE EXTRACTS ON PRESENCE OF ANTIOXIDANT
AND MEMBRANE STABILIZER EFFECT UNDER ENDOGENOUS HYPERLIPIDEMIA

Name of Extracts                                   OChS, mmol/l

1                                                       2

Intact group                                 1.07 [+ or -] 0.03
Controlled group                             1.84 [+ or -] 0.15
Plantago lanceolata (R)                      1.69 [+ or -] 0.15 *
Rosa canina (Sk)                             1.59 [+ or -] 0.25 *
Cratalgus songarica (R)                      1.56 [+ or -] 0.13 *
Cynodon dactulon (R)                         1.90 [+ or -] 0.61 *
Prunus sogdiana (R)                          1.55 [+ or -] 0.26 *
Rosa canina (R)                              1.65 [+ or -] 0.14 *
Crataegus pontica (L)                        1.55 [+ or -] 0.2 *
luniperus zeravshanica (Fr)                  1.32 [+ or -] 0.25
Cynodon dactulon (O)                         1.43 [+ or -] 0.32
Rosa canina (Fr)                             1.63 [+ or -] 0.2 *
Picnomon acarna (O)                          1.91 [+ or -] 0.11 *
Alhagi pseudalhagi (R)                       1.84 [+ or -] 0.16 *
Rosa canina (L)                              1.78 [+ or -] 0.06 *
Prunus sogdiana (Fr)                         1.83 [+ or -] 0.16 *
Chenopodium album (Fr)                       1.96 [+ or -] 0.23 *
Rubus caesius (L)                            1.77 [+ or -] 0.13 *
Chenopodium album (R)                        1.99 [+ or -] 0.2 *
Amaranthus retroplexus (L)                    1.9 [+ or -] 0.04 *
Prunus sogdiana (L)                          1.72 [+ or -] 0.15 *
Amaranthus retroplexus (St)                  1.78 [+ or -] 0.15 *
Amaranthus retroplexus (Fr)                  1.74 [+ or -] 0.12 *
Prunus sogdiana (Sk)                         1.85 [+ or -] 0.11 *
Prunus sogdiana (R)                          1.95 [+ or -] 0.11 *
Prunus sogdiana (O)                          1.68 [+ or -] 0.14 *
Pheum Fedtshenokovi (F)                      1.86 [+ or -] 0.19 *
Atraphaxis pyrifolia (Sk)                    1.89 [+ or -] 0.1 *
Atraphaxis pyrifolia (St)                    1.96 [+ or -] 0.28 *
Atraphaxis pyrifolia (R)                     2.14 [+ or -] 0.08 *
Amygdalis spinosissima (S)                   1.75 [+ or -] 0.05 *
Cerasus erythrocapra (L)                     1.86 [+ or -] 0.12 *
Avena sativa (S)                             0.97 [+ or -] 0.06 **
Amygdalis bucharica (L)                      1.97 [+ or -] 0.23 *
Trifolium pratense (F)                       1.88 [+ or -] 0.04 *
Amygdalis bucharica (Sk)                     1.87 [+ or -] 0.2 *
Pheum Fedtshenokovi (L)                      1.72 [+ or -] 0.1 *
Amygdalis bucharica (L)                      1.65 [+ or -] 0.18 *
Trifolium repens (O)                         1.81 [+ or -] 0.17 *
Solidago dahurica Kitag (O)                  1.72 [+ or -] 0.1 *
Acroptilon repens (L)Op.(O)                  1.73 [+ or -] 0.06 *
Melandrium turkestanicus (Rgl)Vved (R)       1.72 [+ or -] 0.14 *
Inula helenium (R)                           1.81 [+ or -] 0.1 *
Artemisia vulgaris h. (O)                    1.87 [+ or -] 0.03 *
Berberis integerrima (Bge) (Fr)              1.71 [+ or -] 0.12 *
Juniperus turkestanica Kom (L)               1.01 [+ or -] 0.1 **
Solonum nigra h. (Fr)                         2.0 [+ or -] 0.21 *
Solidago dahurica kitag (R)                  1.77 [+ or -] 0.14 *
Melandrium turkestanicus (Rgl)Vved (O)        1.9 [+ or -] 0.06 *
Acroptilon repens (F)                        1.85 [+ or -] 0.14 *
Trifolim pratense h.(F)                      1.67 [+ or -] 0.05 *
Cousinia saawertziwii Regel (O)              1.92 [+ or -] 0.11 *
Anaphalis Velutina Krasch (O)                1.87 [+ or -] 0.13 *
Astragalus sp. (O)                           1.75 [+ or -] 0.08 *
Berberis oblonga (Rgl) Schneid (R)           1.84 [+ or -] 0.05 *
Hieracium procerum Fr (R)                    1.83 [+ or -] 0.16 *
Stachys betoniciflora rupr. (R)              1.84 [+ or -] 0.11 *
Acantholimon erythraeum Bge (A)               1.0 [+ or -] 0.07 **
Pulicaria salviifolia Bunge (R)              1.76 [+ or -] 0.06 *
Psoralea drupacea Bunge (S)                  1.78 [+ or -] 0.18 *
Trifolim pratense h.(O)                      1.74 [+ or -] 0.06 *
Melandrium turkestanicus (Rgl)Vved (Fr)      1.91 [+ or -] 0.13 *
Artemisia vulgaris h. (R)                    1.91 [+ or -] 0.1 *
Descurania Sophia (L) Schur (Fr)             0.98 [+ or -] 0.08 **
Xantium strumarium h. (St)                   1.78 [+ or -] 0.17 *
Conum maculatum h. (St)                      1.78 [+ or -] 0.16 *
Cortusa turkestanica A.Los (O)               1.81 [+ or -] 0.09 *
Tanasetopsis mucronatun S kovalev (O)        1.85 [+ or -] 0.18 *
Xantium strumarium h. (S)                    1.79 [+ or -] 0.08 *
Herniaria glabra h. (O)                      1.76 [+ or -] 0.13 *
Leonurus turkestanicusV.Krecr et Kupr (O)    1.88 [+ or -] 0.09 *
Arctium tomentisum Mill (R)                  1.76 [+ or -] 0.18 *
Ziziphora pedicillate Parii et Vved (R)      1.74 [+ or -]  0.12 *
Solidago dahurica Kitag (F)                   1.7 [+ or -] 0.14 *
Hierasiun procerum Fr (O)                    1.56 [+ or -] 0.06 *
Solonum nigra h. (St)                        1.91 [+ or -] 0.08 *
Agrimonia asiatica lus (R)                   1.83 [+ or -] 0.05 *
Xantium strumarium h.(R)                     1.82 [+ or -] 0.06 *
Cortusa turkestanica A. Los (F)              1.99 [+ or -] 0.08 *
Artemisia vilgaris L.(F)                     1.67 [+ or -] 0.04 *
Chamenerium angustibolium (L) Scop (R)       1.82 [+ or -] 0.13 *
Stachyopsys oblongata M. Popet Vved (O)      1.84 [+ or -] 0.05 *
Stachys betoniciflora Rupr (F)                1.9 [+ or -] 0.18 *
Ziziphora pedicillate Parii et Vved (St)     1.73 [+ or -] 0.1 *
Spiraea pilosa Franch (O)                    1.93 [+ or -] 0.05 *
Acroptilon repens (R)                        1.65 [+ or -] 0.12 *
Solonum nigra h. (R)                         1.78 [+ or -] 0.16 *
Phragmites communis Trin (St)                1.89 [+ or -] 0.07 *
Cortusa turkestanica A. hos (R)               1.8 [+ or -] 0.03 *
Trigonella pamirica Boriss (A)                1.0 [+ or -] 0.12 **
Astragalus sp. (R)                           1.86 [+ or -] 0.17 *
Trifolium pratense L. (R)                    1.73 [+ or -] 0.13 *
Solonum nigra h. (L)                         1.79 [+ or -] 0.2 *
Pulicaria salviibolia Binge (St)             1.49 [+ or -] 0.17
Phragmites communis Tren (L)                 1.75 [+ or -] 0.6 *
Phragmites communis Trin (R)                 1.69 [+ or -] 0.16 *
Oberna beechen (L) Ikonn (Fr)                1.68 [+ or -] 0.15 *
Agrimonia ariatica lus (L)                   1.83 [+ or -] 0.13 *
Serophularia umbrosa Dumort (St)             1.91 [+ or -] 0.1 *
Serophularia umbrosa Dumort (O)              1.69 [+ or -] 0.13 *
Siderities montana L (St)                    1.89 [+ or -] 0.12 *
Phlomis olgae Rgl (R)                        1.01 [+ or -] 0.1 **
Serratula alatavica c.A.M. (F)               1.83 [+ or -] 0.11 *
Serratula alatavica c.A.M.(O)                1.89 [+ or -] 0.08 *
Inula helenium L (F)                         1.66 [+ or -] 0.04 *
Psoralea drupacea Bunge (R)                  1.77 [+ or -] 0.2 *
Inula helenium L (L)                          1.8 [+ or -] 0.19 *
Phlomis sewerzowii Rgl (O)                   1.38 [+ or -] 0.17 *

Name of Extracts                                    TG, mmol/l

1                                                       3

Intact group                                 0.72 [+ or -] 0.041
Controlled group                             1.03 [+ or -] 0.05
Plantago lanceolata (R)                      1.03 [+ or -] 0.12 *
Rosa canina (Sk)                             1.08 [+ or -] 0.05 *
Cratalgus songarica (R)                      1.11 [+ or -] 0.19 *
Cynodon dactulon (R)                         1.07 [+ or -] 0.12 *
Prunus sogdiana (R)                          0.97 [+ or -] 0.12 *
Rosa canina (R)                              0.94 [+ or -] 0.1 *
Crataegus pontica (L)                        1.06 [+ or -] 0.06 *
luniperus zeravshanica (Fr)                  0.96 [+ or -] 0.03 *
Cynodon dactulon (O)                         1.07 [+ or -] 0.05 *
Rosa canina (Fr)                             0.92 [+ or -] 0.09 *
Picnomon acarna (O)                          0.96 [+ or -] 0.13 *
Alhagi pseudalhagi (R)                       1.01 [+ or -] 0.09 *
Rosa canina (L)                              0.95 [+ or -] 0.13 *
Prunus sogdiana (Fr)                         0.95 [+ or -] 0.15 *
Chenopodium album (Fr)                       1.07 [+ or -] 0.02 *
Rubus caesius (L)                            0.89 [+ or -] 0.09
Chenopodium album (R)                        0.94 [+ or -] 0.05 *
Amaranthus retroplexus (L)                   1.01 [+ or -] 0.04 *
Prunus sogdiana (L)                          0.89 [+ or -] 0.1
Amaranthus retroplexus (St)                  0.89 [+ or -] 0.07
Amaranthus retroplexus (Fr)                   0.9 [+ or -] 0.06
Prunus sogdiana (Sk)                         0.98 [+ or -] 0.05 *
Prunus sogdiana (R)                          1.01 [+ or -] 0.08 *
Prunus sogdiana (O)                          0.97 [+ or -] 0.14 *
Pheum Fedtshenokovi (F)                      0.98 [+ or -] 0.11 *
Atraphaxis pyrifolia (Sk)                    1.06 [+ or -] 0.09 *
Atraphaxis pyrifolia (St)                    1.04 [+ or -] 0.04 *
Atraphaxis pyrifolia (R)                     0.89 [+ or -] 0.08
Amygdalis spinosissima (S)                   0.95 [+ or -] 0.18 *
Cerasus erythrocapra (L)                     0.96 [+ or -] 0.06 *
Avena sativa (S)                             0.66 [+ or -] 0.08 **
Amygdalis bucharica (L)                      1.04 [+ or -] 0.19 *
Trifolium pratense (F)                       0.94 [+ or -] 0.11 *
Amygdalis bucharica (Sk)                     0.86 [+ or -] 0.08
Pheum Fedtshenokovi (L)                      0.93 [+ or -] 0.06 *
Amygdalis bucharica (L)                       0.9 [+ or -] 0.17
Trifolium repens (O)                         0.94 [+ or -] 0.09 *
Solidago dahurica Kitag (O)                  0.96 [+ or -] 0.08 *
Acroptilon repens (L)Op.(O)                  0.95 [+ or -] 0.07 *
Melandrium turkestanicus (Rgl)Vved (R)       0.94 [+ or -] 0.07 *
Inula helenium (R)                           1.03 [+ or -] 0.11 *
Artemisia vulgaris h. (O)                    0.98 [+ or -] 0.04 *
Berberis integerrima (Bge) (Fr)              0.93 [+ or -] 0.1 *
Juniperus turkestanica Kom (L)               0.72 [+ or -] 0.05 **
Solonum nigra h. (Fr)                        0.98 [+ or -] 0.11 *
Solidago dahurica kitag (R)                  0.98 [+ or -] 0.12 *
Melandrium turkestanicus (Rgl)Vved (O)       0.98 [+ or -] 0.08 *
Acroptilon repens (F)                        0.83 [+ or -] 0.06
Trifolim pratense h.(F)                      1.01 [+ or -] 0.09 *
Cousinia saawertziwii Regel (O)              1.05 [+ or -] 0.21 *
Anaphalis Velutina Krasch (O)                0.94 [+ or -] 0.06 *
Astragalus sp. (O)                           1.12 [+ or -] 0.05 *
Berberis oblonga (Rgl) Schneid (R)           0.96 [+ or -] 0.03 *
Hieracium procerum Fr (R)                    0.92 [+ or -] 0.11 *
Stachys betoniciflora rupr. (R)              0.96 [+ or -] 0.2 *
Acantholimon erythraeum Bge (A)              0.79 [+ or -] 0.06 **
Pulicaria salviifolia Bunge (R)              1.02 [+ or -] 0.1 *
Psoralea drupacea Bunge (S)                  1.01 [+ or -] 0.2 *
Trifolim pratense h.(O)                      0.99 [+ or -] 0.09 *
Melandrium turkestanicus (Rgl)Vved (Fr)       1.1 [+ or -] 0.17 *
Artemisia vulgaris h. (R)                    1.13 [+ or -] 0.25 *
Descurania Sophia (L) Schur (Fr)             0.73 [+ or -] 0.06 **
Xantium strumarium h. (St)                   0.85 [+ or -] 0.07
Conum maculatum h. (St)                      0.91 [+ or -] 0.05 *
Cortusa turkestanica A.Los (O)               0.89 [+ or -] 0.06
Tanasetopsis mucronatun S kovalev (O)         0.9 [+ or -] 0.06 *
Xantium strumarium h. (S)                    0.81 [+ or -] 0.1
Herniaria glabra h. (O)                      0.84 [+ or -] 0.05
Leonurus turkestanicusV.Krecr et Kupr (O)    0.91 [+ or -] 0.1 *
Arctium tomentisum Mill (R)                   1.1 [+ or -] 0.04 *
Ziziphora pedicillate Parii et Vved (R)      0.93 [+ or -] 0.11 *
Solidago dahurica Kitag (F)                  0.93 [+ or -] 0.1 *
Hierasiun procerum Fr (O)                    0.91 [+ or -] 0.06 *
Solonum nigra h. (St)                        0.98 [+ or -] 0.13 *
Agrimonia asiatica lus (R)                   0.92 [+ or -] 0.12 *
Xantium strumarium h.(R)                     0.91 [+ or -] 0.11 *
Cortusa turkestanica A. Los (F)              1.04 [+ or -] 0.14 *
Artemisia vilgaris L.(F)                     0.93 [+ or -] 0.06 *
Chamenerium angustibolium (L) Scop (R)       1.04 [+ or -] 0.12 *
Stachyopsys oblongata M. Popet Vved (O)       0.9 [+ or -] 0.09 *
Stachys betoniciflora Rupr (F)                1.0 [+ or -] 0.1 *
Ziziphora pedicillate Parii et Vved (St)     0.96 [+ or -] 0.11 *
Spiraea pilosa Franch (O)                    0.94 [+ or -] 0.11 *
Acroptilon repens (R)                        0.84 [+ or -] 0.04
Solonum nigra h. (R)                         1.03 [+ or -] 0.1 *
Phragmites communis Trin (St)                1.14 [+ or -] 0.09 *
Cortusa turkestanica A. hos (R)              0.86 [+ or -] 0.08 *
Trigonella pamirica Boriss (A)               0.76 [+ or -] 0.74 **
Astragalus sp. (R)                           0.98 [+ or -] 0.13 *
Trifolium pratense L. (R)                    0.98 [+ or -] 0.24 *
Solonum nigra h. (L)                         0.96 [+ or -] 0.15 *
Pulicaria salviibolia Binge (St)             0.69 [+ or -] 0.1 **
Phragmites communis Tren (L)                 0.94 [+ or -] 0.1 *
Phragmites communis Trin (R)                 0.98 [+ or -] 0.15 *
Oberna beechen (L) Ikonn (Fr)                0.78 [+ or -] 0.06 **
Agrimonia ariatica lus (L)                   1.07 [+ or -] 0.13 *
Serophularia umbrosa Dumort (St)             1.07 [+ or -] 0.06 *
Serophularia umbrosa Dumort (O)              0.85 [+ or -] 0.18
Siderities montana L (St)                    0.94 [+ or -] 0.1 *
Phlomis olgae Rgl (R)                        0.74 [+ or -] 0.07 **
Serratula alatavica c.A.M. (F)               1.03 [+ or -] 0.16 *
Serratula alatavica c.A.M.(O)                0.97 [+ or -] 0.08 *
Inula helenium L (F)                         0.95 [+ or -] 0.13 *
Psoralea drupacea Bunge (R)                  0.96 [+ or -] 0.17 *
Inula helenium L (L)                         1.06 [+ or -] 0.08 *
Phlomis sewerzowii Rgl (O)                   0.96 [+ or -] 0.16 *

Name of Extracts                                 ChS HDL, mmol/l

1                                                       4

Intact group                                  0.6 [+ or -] 0.077
Controlled group                             0.47 [+ or -] 0.033
Plantago lanceolata (R)                      0.39 [+ or -] 0.04 *
Rosa canina (Sk)                             0.35 [+ or -] 0.08 *
Cratalgus songarica (R)                      0.35 [+ or -] 0.06 *
Cynodon dactulon (R)                         0.33 [+ or -] 0.11 *
Prunus sogdiana (R)                          0.39 [+ or -] 0.03 *
Rosa canina (R)                              0.37 [+ or -] 0.11 *
Crataegus pontica (L)                         0.4 [+ or -] 0.08 *
luniperus zeravshanica (Fr)                  0.39 [+ or -] 0.09 *
Cynodon dactulon (O)                         0.35 [+ or -] 0.05 *
Rosa canina (Fr)                             0.45 [+ or -] 0.01 *
Picnomon acarna (O)                          0.43 [+ or -] 0.05 *
Alhagi pseudalhagi (R)                       0.48 [+ or -] 0.08
Rosa canina (L)                              0.44 [+ or -] 0.04
Prunus sogdiana (Fr)                         0.44 [+ or -] 0.08
Chenopodium album (Fr)                       0.42 [+ or -] 0.06
Rubus caesius (L)                            0.45 [+ or -] 0.09
Chenopodium album (R)                        0.38 [+ or -] 0.02 *
Amaranthus retroplexus (L)                   0.35 [+ or -] 0.06 *
Prunus sogdiana (L)                          0.47 [+ or -] 0.09
Amaranthus retroplexus (St)                  0.41 [+ or -] 0.07
Amaranthus retroplexus (Fr)                  0.49 [+ or -] 0.17
Prunus sogdiana (Sk)                         0.47 [+ or -] 0.08
Prunus sogdiana (R)                          0.48 [+ or -] 0.07
Prunus sogdiana (O)                          0.47 [+ or -] 0.07
Pheum Fedtshenokovi (F)                      0.43 [+ or -] 0.07
Atraphaxis pyrifolia (Sk)                    0.45 [+ or -] 0.02
Atraphaxis pyrifolia (St)                    0.51 [+ or -] 0.1
Atraphaxis pyrifolia (R)                     0.39 [+ or -] 0.11 *
Amygdalis spinosissima (S)                   0.43 [+ or -] 0.06
Cerasus erythrocapra (L)                     0.35 [+ or -] 0.03 *
Avena sativa (S)                             0.54 [+ or -] 0.05 **
Amygdalis bucharica (L)                      0.35 [+ or -] 0.04 *
Trifolium pratense (F)                       0.43 [+ or -] 0.03
Amygdalis bucharica (Sk)                     0.43 [+ or -] 0.11
Pheum Fedtshenokovi (L)                      0.42 [+ or -] 0.02
Amygdalis bucharica (L)                      0.45 [+ or -] 0.04
Trifolium repens (O)                         0.46 [+ or -] 0.02
Solidago dahurica Kitag (O)                  0.45 [+ or -] 0.08
Acroptilon repens (L)Op.(O)                  0.36 [+ or -] 0.03 *
Melandrium turkestanicus (Rgl)Vved (R)       0.46 [+ or -] 0.04
Inula helenium (R)                           0.45 [+ or -] 0.02
Artemisia vulgaris h. (O)                    0.37 [+ or -] 0.06 *
Berberis integerrima (Bge) (Fr)              0.35 [+ or -] 0.06 *
Juniperus turkestanica Kom (L)               0.56 [+ or -] 0.03
Solonum nigra h. (Fr)                        0.42 [+ or -] 0.06
Solidago dahurica kitag (R)                   0.4 [+ or -] 0.02 *
Melandrium turkestanicus (Rgl)Vved (O)       0.42 [+ or -] 0.06
Acroptilon repens (F)                        0.35 [+ or -] 0.07 *
Trifolim pratense h.(F)                      0.42 [+ or -] 0.06
Cousinia saawertziwii Regel (O)              0.44 [+ or -] 0.06
Anaphalis Velutina Krasch (O)                0.43 [+ or -] 0.02
Astragalus sp. (O)                           0.44 [+ or -] 0.06
Berberis oblonga (Rgl) Schneid (R)           0.39 [+ or -] 0.01 *
Hieracium procerum Fr (R)                    0.46 [+ or -] 0.07
Stachys betoniciflora rupr. (R)              0.46 [+ or -] 0.04
Acantholimon erythraeum Bge (A)              0.55 [+ or -] 0.05 **
Pulicaria salviifolia Bunge (R)              0.45 [+ or -] 0.09
Psoralea drupacea Bunge (S)                  0.47 [+ or -] 0.03
Trifolim pratense h.(O)                      0.41 [+ or -] 0.05
Melandrium turkestanicus (Rgl)Vved (Fr)      0.38 [+ or -] 0.07 *
Artemisia vulgaris h. (R)                    0.43 [+ or -] 0.05
Descurania Sophia (L) Schur (Fr)             0.53 [+ or -] 0.04 **
Xantium strumarium h. (St)                   0.45 [+ or -] 0.04
Conum maculatum h. (St)                      0.44 [+ or -] 0.05
Cortusa turkestanica A.Los (O)               0.38 [+ or -] 0.04 *
Tanasetopsis mucronatun S kovalev (O)         0.5 [+ or -] 0.1
Xantium strumarium h. (S)                    0.37 [+ or -] 0.09 *
Herniaria glabra h. (O)                      0.37 [+ or -] 0.04 *
Leonurus turkestanicusV.Krecr et Kupr (O)    0.44 [+ or -] 0.12
Arctium tomentisum Mill (R)                  0.46 [+ or -] 0.07
Ziziphora pedicillate Parii et Vved (R)      0.39 [+ or -] 0.07 *
Solidago dahurica Kitag (F)                  0.47 [+ or -] 0.03
Hierasiun procerum Fr (O)                    0.37 [+ or -] 0.18 *
Solonum nigra h. (St)                        0.44 [+ or -] 0.03
Agrimonia asiatica lus (R)                   0.33 [+ or -] 0.07 *
Xantium strumarium h.(R)                     0.34 [+ or -] 0.07 *
Cortusa turkestanica A. Los (F)              0.52 [+ or -] 0.06
Artemisia vilgaris L.(F)                     0.42 [+ or -] 0.06
Chamenerium angustibolium (L) Scop (R)        0.4 [+ or -] 0.17 *
Stachyopsys oblongata M. Popet Vved (O)      0.51 [+ or -] 0.1
Stachys betoniciflora Rupr (F)               0.54 [+ or -] 0.15 **
Ziziphora pedicillate Parii et Vved (St)     0.49 [+ or -] 0.08
Spiraea pilosa Franch (O)                    0.38 [+ or -] 0.05 *
Acroptilon repens (R)                        0.36 [+ or -] 0.07 *
Solonum nigra h. (R)                         0.52 [+ or -] 0.08
Phragmites communis Trin (St)                0.51 [+ or -] 0.1
Cortusa turkestanica A. hos (R)               0.4 [+ or -] 0.02 *
Trigonella pamirica Boriss (A)               0.54 [+ or -] 0.08
Astragalus sp. (R)                           0.34 [+ or -] 0.08 *
Trifolium pratense L. (R)                    0.42 [+ or -] 0.11
Solonum nigra h. (L)                         0.41 [+ or -] 0.05
Pulicaria salviibolia Binge (St)              0.4 [+ or -] 0.04 *
Phragmites communis Tren (L)                 0.45 [+ or -] 0.16
Phragmites communis Trin (R)                 0.41 [+ or -] 0.08
Oberna beechen (L) Ikonn (Fr)                0.46 [+ or -] 0.08
Agrimonia ariatica lus (L)                   0.44 [+ or -] 0.05
Serophularia umbrosa Dumort (St)             0.32 [+ or -] 0.08 *

Serophularia umbrosa Dumort (O)              0.54 [+ or -] 0.15 **
Siderities montana L (St)                    0.43 [+ or -] 0.06
Phlomis olgae Rgl (R)                        0.54 [+ or -] 0.06 **
Serratula alatavica c.A.M. (F)               0.38 [+ or -] 0.07 *
Serratula alatavica c.A.M.(O)                0.37 [+ or -] 0.07 *
Inula helenium L (F)                         0.43 [+ or -] 0.04
Psoralea drupacea Bunge (R)                  0.45 [+ or -] 0.11
Inula helenium L (L)                         0.43 [+ or -] 0.1
Phlomis sewerzowii Rgl (O)                   0.47 [+ or -] 0.01

Name of Extracts                                     OL, g/l

1                                                       5

Intact group                                 4.35 [+ or -] 0.17
Controlled group                             6.61 [+ or -] 0.26
Plantago lanceolata (R)                      7.35 [+ or -] 0.18 *. **
Rosa canina (Sk)                             7.28 [+ or -] 0.49 *
Cratalgus songarica (R)                      8.07 [+ or -] 0.17 *. **
Cynodon dactulon (R)                         5.82 [+ or -] 0.31
Prunus sogdiana (R)                          8.34 [+ or -] 0.96 *. **
Rosa canina (R)                               5.3 [+ or -] 0.22
Crataegus pontica (L)                        7.68 [+ or -] 0.65 *. **
luniperus zeravshanica (Fr)                   7.3 [+ or -] 0.72 *
Cynodon dactulon (O)                          5.9 [+ or -] 0.6
Rosa canina (Fr)                             5.89 [+ or -] 0.39
Picnomon acarna (O)                          6.97 [+ or -] 0.91 *
Alhagi pseudalhagi (R)                       7.46 [+ or -] 0.75 *. **
Rosa canina (L)                              7.79 [+ or -] 0.96 *. **
Prunus sogdiana (Fr)                         7.43 [+ or -] 0.9 *. **
Chenopodium album (Fr)                       5.37 [+ or -] 0.85
Rubus caesius (L)                             7.3 [+ or -] 1.4 *
Chenopodium album (R)                         6.3 [+ or -] 0.39 *
Amaranthus retroplexus (L)                   6.74 [+ or -] 0.97 *
Prunus sogdiana (L)                          7.23 [+ or -] 2.08 *
Amaranthus retroplexus (St)                  5.23 [+ or -] 1.15
Amaranthus retroplexus (Fr)                  6.94 [+ or -] 1.17 *
Prunus sogdiana (Sk)                         5.42 [+ or -] 1.35
Prunus sogdiana (R)                           5.9 [+ or -] 1.59 *
Prunus sogdiana (O)                          7.32 [+ or -] 0.59 *
Pheum Fedtshenokovi (F)                      5.54 [+ or -] 1.41
Atraphaxis pyrifolia (Sk)                    5.26 [+ or -] 0.5
Atraphaxis pyrifolia (St)                    6.08 [+ or -] 0.55 *
Atraphaxis pyrifolia (R)                     7.79 [+ or -] 1.03 *
Amygdalis spinosissima (S)                   6.32 [+ or -] 1.1 *
Cerasus erythrocapra (L)                     7.89 [+ or -] 0.69 *
Avena sativa (S)                             4.21 [+ or -] 0.13 **
Amygdalis bucharica (L)                      6.89 [+ or -] 0.96 *
Trifolium pratense (F)                       5.87 [+ or -] 1.35
Amygdalis bucharica (Sk)                     4.22 [+ or -] 0.57 **
Pheum Fedtshenokovi (L)                      4.87 [+ or -] 0.89 **
Amygdalis bucharica (L)                      7.47 [+ or -] 0.86 *
Trifolium repens (O)                         6.48 [+ or -] 1.0 *
Solidago dahurica Kitag (O)                   7.4 [+ or -] 0.49 *
Acroptilon repens (L)Op.(O)                 6.458 [+ or -] 0.8 *
Melandrium turkestanicus (Rgl)Vved (R)       7.55 [+ or -] 0.79 *
Inula helenium (R)                           7.42 [+ or -] 1.26 *
Artemisia vulgaris h. (O)                    7.75 [+ or -] 1.67 *
Berberis integerrima (Bge) (Fr)              7.89 [+ or -] 0.94 *
Juniperus turkestanica Kom (L)               4.59 [+ or -] 0.22 **
Solonum nigra h. (Fr)                        5.28 [+ or -] 1.39
Solidago dahurica kitag (R)                  6.51 [+ or -] 1.31 *
Melandrium turkestanicus (Rgl)Vved (O)       5.09 [+ or -] 1.73
Acroptilon repens (F)                         5.1 [+ or -] 0.954
Trifolim pratense h.(F)                      7.03 [+ or -] 1.2 *
Cousinia saawertziwii Regel (O)              7.09 [+ or -] 0.49 *
Anaphalis Velutina Krasch (O)                4.96 [+ or -] 0.98 **
Astragalus sp. (O)                           7.68 [+ or -] 0.34 *
Berberis oblonga (Rgl) Schneid (R)           6.29 [+ or -] 0.48 *
Hieracium procerum Fr (R)                    6.98 [+ or -] 1.31 *
Stachys betoniciflora rupr. (R)              4.96 [+ or -] 1.49 **
Acantholimon erythraeum Bge (A)              4.64 [+ or -] 0.48 **
Pulicaria salviifolia Bunge (R)              7.85 [+ or -] 2.16 *
Psoralea drupacea Bunge (S)                  7.91 [+ or -] 1.43 *
Trifolim pratense h.(O)                      6.48 [+ or -] 0.48 *
Melandrium turkestanicus (Rgl)Vved (Fr)      5.48 [+ or -] 0.57
Artemisia vulgaris h. (R)                    6.94 [+ or -] 0.37 *
Descurania Sophia (L) Schur (Fr)             4.39 [+ or -] 0.39 **
Xantium strumarium h. (St)                    7.8 [+ or -] 0.27 *
Conum maculatum h. (St)                      6.56 [+ or -] 0.49 *
Cortusa turkestanica A.Los (O)                6.2 [+ or -] 1.0 *
Tanasetopsis mucronatun S kovalev (O)        6.43 [+ or -] 0.1 *
Xantium strumarium h. (S)                     7.8 [+ or -] 0.3 *
Herniaria glabra h. (O)                      7.98 [+ or -] 1.04 *
Leonurus turkestanicusV.Krecr et Kupr (O)    6.57 [+ or -] 0.91 *
Arctium tomentisum Mill (R)                  4.57 [+ or -] 0.87 **
Ziziphora pedicillate Parii et Vved (R)      8.38 [+ or -] 1.2 *
Solidago dahurica Kitag (F)                   7.2 [+ or -] 0.6 *
Hierasiun procerum Fr (O)                    6.17 [+ or -] 0.51 *
Solonum nigra h. (St)                        7.45 [+ or -] 0.82 *
Agrimonia asiatica lus (R)                   6.41 [+ or -] 1.24 *
Xantium strumarium h.(R)                     5.29 [+ or -] 1.3
Cortusa turkestanica A. Los (F)              5.88 [+ or -] 1.44
Artemisia vilgaris L.(F)                      6.5 [+ or -] 0.21 *
Chamenerium angustibolium (L) Scop (R)       6.91 [+ or -] 0.51 *
Stachyopsys oblongata M. Popet Vved (O)      8.02 [+ or -] 0.79 *
Stachys betoniciflora Rupr (F)               6.11 [+ or -] 0.82 *
Ziziphora pedicillate Parii et Vved (St)     7.56 [+ or -] 0.82 *
Spiraea pilosa Franch (O)                    7.83 [+ or -] 1.02 *
Acroptilon repens (R)                        7.39 [+ or -] 1.3 *
Solonum nigra h. (R)                         6.01 [+ or -] 1.1 *
Phragmites communis Trin (St)                6.78 [+ or -] 0.23 *
Cortusa turkestanica A. hos (R)              4.29 [+ or -] 0.97 **
Trigonella pamirica Boriss (A)               4.54 [+ or -] 0.57 **
Astragalus sp. (R)                           7.53 [+ or -] 0.76 *
Trifolium pratense L. (R)                    7.98 [+ or -] 0.62 *
Solonum nigra h. (L)                          6.7 [+ or -] 0.41 *
Pulicaria salviibolia Binge (St)             5.84 [+ or -] 1.46
Phragmites communis Tren (L)                 5.94 [+ or -] 1.29
Phragmites communis Trin (R)                 6.24 [+ or -] 1.0 *
Oberna beechen (L) Ikonn (Fr)                7.69 [+ or -] 0.51 *
Agrimonia ariatica lus (L)                   8.33 [+ or -] 0.39 *
Serophularia umbrosa Dumort (St)             7.19 [+ or -] 1.13 *
Serophularia umbrosa Dumort (O)              8.04 [+ or -] 0.7 *
Siderities montana L (St)                    6.01 [+ or -] 0.73 *
Phlomis olgae Rgl (R)                         4.5 [+ or -] 0.22 **
Serratula alatavica c.A.M. (F)               4.84 [+ or -] 0.52 **
Serratula alatavica c.A.M.(O)                7.15 [+ or -] 0.68 *
Inula helenium L (F)                          7.6 [+ or -] 1.18 *
Psoralea drupacea Bunge (R)                  8.99 [+ or -] 0.4 *
Inula helenium L (L)                         7.05 [+ or -] 1.09 *
Phlomis sewerzowii Rgl (O)                   6.24 [+ or -] 0.5 *

Note: F--flower; R--root; S--seed; FR--fruit; L--leaves;
St--stem; O--overground part; Sk--skin; E--entire plant;
I--inflorescence; A--upper part of overground part. Authentic
difference P<0,05: *--from intact group; **--from controlled
group

TABLE 2. THE SCREENING OF VEGETABLE EXTRACTS ON PRESENCE OF
HYPOLIPIDEMIC EFFECT UNDER ENDOGENOUS HYPERLIPIDEMIA

Name of Extracts                                   CP, mg/100 ml
                    1                                    2

Intact group                                 16.82 [+ or -] 2.24
Controlled group                             13.08 [+ or -] 1.38
Plantago lanceolata (R)                      11.75 [+ or -] 2.19 *
Rosa canina (Sk)                             13.69 [+ or -] 3.3
Cratalgus songarica (R)                      10.96 [+ or -] 2.84 *
Cynodon dactulon (R)                         12.82 [+ or -] 2.35 *
Prunus sogdiana (R)                            8.4 [+ or -] 1.74 *. **
Rosa canina (R)                               8.91 [+ or -] 1.39 *
Crataegus pontica (L)                        10.17 [+ or -] 2.69 *
luniperus zeravshanica (Fr)                  12.37 [+ or -] 3.48 *
Cynodon dactulon (O)                         17.37 [+ or -] 3.7 **
Rosa canina (Fr)                             15.99 [+ or -] 2.7 **
Picnomon acarna (O)                          15.89 [+ or -] 2.38 **
Alhagi pseudalhagi (R)                        8.25 [+ or -] 1.98 *. **
Rosa canina (L)                              10.59 [+ or -] 1.59 *
Prunus sogdiana (Fr)                         16.08 [+ or -] 3.08 **
Chenopodium album (Fr)                       14.19 [+ or -] 2.26
Rubus caesius (L)                             6.73 [+ or -] 2.34 *. **
Chenopodium album (R)                        13.15 [+ or -] 2.01 *
Amaranthus retroplexus (L)                    9.46 [+ or -] 1.99 *
Prunus sogdiana (L)                          10.98 [+ or -] 2.0 *
Amaranthus retroplexus (St)                  13.72 [+ or -] 3.48 *
Amaranthus retroplexus (Fr)                   6.72 [+ or -] 1.81 *. **
Prunus sogdiana (Sk)                          12.8 [+ or -] 2.95 *
Prunus sogdiana (R)                           13.3 [+ or -] 1.54
Prunus sogdiana (O)                           9.45 [+ or -] 2.18 *
Pheum Fedtshenokovi (F)                       6.89 [+ or -] 2.92 *. **
Atraphaxis pyrifolia (Sk)                     6.36 [+ or -] 1.31 *. **
Atraphaxis pyrifolia (St)                     6.56 [+ or -] 1.15 *. **
Atraphaxis pyrifolia (R)                      8.73 [+ or -] 4.59 *
Amygdalis spinosissima (S)                    7.89 [+ or -] 1.6 *
Cerasus erythrocapra (L)                     10.62 [+ or -] 1.48 *
Avena sativa (S)                             17.46 [+ or -] 1.04 **
Amygdalis bucharica (L)                       6.31 [+ or -] 2.17 *. **
Trifolium pratense (F)                       10.62 [+ or -] 1.84 *
Amygdalis bucharica (Sk)                     14.53 [+ or -] 2.89
Pheum Fedtshenokovi (L)                      11.72 [+ or -] 1.84 *
Amygdalis bucharica (L)                      11.52 [+ or -] 3.26 *
Trifolium repens (O)                          7.71 [+ or -] 1.49 *
Solidago dahurica Kitag (O)                  12.44 [+ or -] 1.69 *
Acroptilon repens (L)Op.(O)                   6.48 [+ or -] 1.71 *. **
Melandrium turkestanicus (Rgl)Vved (R)       14.31 [+ or -] 4.31
Inula helenium (R)                            13.9 [+ or -] 2.7
Artemisia vulgaris h. (O)                     8.24 [+ or -] 1.18 *
Berberis integerrima (Bge) (Fr)               14.1 [+ or -] 3.13
Juniperus turkestanica Kom (L)               15.03 [+ or -] 2.59 **
Solonum nigra h. (Fr)                        16.88 [+ or -] 1.31 **
Solidago dahurica Kitag (O)                  15.02 [+ or -] 3.88 **
Melandrium turkestanicus (Rgl)Vved (O)         7.5 [+ or -] 1.27 *
Acroptilon repens (F)                          8.0 [+ or -] 2.77 *
Trifolim pratense h.(F)                      13.51 [+ or -] 1.34
Cousinia saawertziwii Regel (O)               6.07 [+ or -] 1.93 *. **
Anaphalis Velutina Krasch (O)                14.71 [+ or -] 2.16
Astragalus sp. (O)                            9.67 [+ or -] 2.02 *
Berberis oblonga (Rgl) Schneid [R]           10.35 [+ or -] 1.85 *
Hieracium procerum Fr [R]                    12.49 [+ or -] 3.59 *
Stachys betoniciflora rupr. [R]               9.58 [+ or -] 0.6 *
Acantholimon erythraeum Bge (A)              14.55 [+ or -] 1.96
Pulicaria salviifolia Bunge (R)              14.62 [+ or -] 1.69
Psoralea drupacea Bunge (S)                  15.57 [+ or -] 1.49
Trifolim pratense h.(O)                       8.32 [+ or -] 2.85 *
Melandrium turkestanicus (Rgl)Vved (Fr)       8.84 [+ or -] 2.65 *
Artemisia vulgaris h. (R)                    13.47 [+ or -] 1.84
Descurania Sophia (L) Schur (Fr)             15.79 [+ or -] 1.95
Xantium strumarium h. (St)                   17.37 [+ or -] 2.51 **
Conum maculatum h. (St)                      13.47 [+ or -] 3.42
Cortusa turkestanica A.Los (O)                9.68 [+ or -] 3.0 *
Tanasetopsis mucronatun S kovalev (O)         14.9 [+ or -] 2.61
Xantium strumarium h. (S)                     18.1 [+ or -] 5.48 **
Herniaria glabra h. (O)                       13.4 [+ or -] 3.55
Leonurus turkestanicusV.Krecr et Kupr (O)    11.85 [+ or -] 1.52 *
Arctium tomentisum Mill (R)                  11.62 [+ or -] 2.92 *
Ziziphora pedicillate Parii et Vved (R)        7.8 [+ or -] 0.69 *
Solidago dahurica Kitag (F)                  12.84 [+ or -] 1.61 *
Hierasiun procerum Fr (O)                     10.5 [+ or -] 3.06 *
Solonum nigra h. (St)                         9.48 [+ or -] 11.13 *
Agrimonia asiatica lus (R)                    9.33 [+ or -] 0.15 *
Xantium strumarium h.(R)                      9.33 [+ or -] 2.15 *
Cortusa turkestanica A. Los (F)               6.65 [+ or -] 1.88 *. *
Artemisia vilgaris L.(F)                      11.6 [+ or -] 1.71 *
Chamenerium angustibolium (L) Scop (R)        7.16 [+ or -] 2.11 *
Stachyopsys oblongata M. Popet Vved (O)       8.63 [+ or -] 2.84 *
Stachys betoniciflora Rupr (F)               11.37 [+ or -] 2.17 *
Ziziphora pedicillate Parii et Vved (St)     17.58 [+ or -] 2.28 **
Spiraea pilosa Franch (O)                    12.63 [+ or -] 2.47 *
Acroptilon repens (R)                        10.10 [+ or -] 2.11 *
Solonum nigra h. (R)                          5.79 [+ or -] 1.01 *. **
Phragmites communis Trin (St)                 15.2 [+ or -] 0.66
Cortusa turkestanica A. hos (R)               14.2 [+ or -] 2.92
Trigonella pamirica Boriss (A)               20.74 [+ or -] 1.11 *. **
Astragalus sp. (R)                            13.4 [+ or -] 2.11
Trifolium pratense L. (R)                    15.72 [+ or -] 2.54
Solonum nigra h. (L)                         15.07 [+ or -] 2.24
Pulicaria salviibolia Binge (St)              7.09 [+ or -] 1.26 *
Phragmites communis Tren (L)                  5.64 [+ or -] 1.19 *. **
Phragmites communis Trin (R)                  8.83 [+ or -] 1.85 *
Oberna beechen (L) Ikonn (Fr)                 7.38 [+ or -] 2.02 *
Agrimonia ariatica lus (L)                   16.69 [+ or -] 2.45 **
Serophularia umbrosa Dumort (St)              8.25 [+ or -] 2.2 *
Serophularia umbrosa Dumort (O)               7.86 [+ or -] 1.93 *
Siderities montana L (St)                    12.21 [+ or -] 1.66 *
Phlomis olgae Rgl (R)                        16.54 [+ or -] 1.87 **
Serratula alatavica c.A.M. (F)                7.62 [+ or -] 3.53 *
Serratula alatavica c.A.M.(O)                12.36 [+ or -] 1.59 *
Inula helenium L (F)                         12.12 [+ or -] 1.75 *
Psoralea drupacea Bunge (R)                  12.11 [+ or -] 1.96 *
Inula helenium L (L)                          5.82 [+ or -] 1.73 *. **
Phlomis sewerzowii Rgl (O)                   11.24 [+ or -] 3.41 *

Name of Extracts                                     PHE, %
                    1                                  3

Intact group                                 13.87 [+ or -] 0.66
Controlled group                             16.18 [+ or -] 0.12
Plantago lanceolata (R)                       15.4 [+ or -] 0.11
Rosa canina (Sk)                              14.0 [+ or -] 0.08
Cratalgus songarica (R)                       16.0 [+ or -] 0.1
Cynodon dactulon (R)                         12.13 [+ or -] 0.1
Prunus sogdiana (R)                           13.2 [+ or -] 0.13
Rosa canina (R)                               14.9 [+ or -] 0.1
Crataegus pontica (L)                         15.2 [+ or -] 0.13
luniperus zeravshanica (Fr)                   17.1 [+ or -] 0.1
Cynodon dactulon (O)                          18.1 [+ or -] 0.09 *
Rosa canina (Fr)                             17. 0 [+ or -] 0.11
Picnomon acarna (O)                           13.1 [+ or -] 0.21
Alhagi pseudalhagi (R)                        13.2 [+ or -] 1.05
Rosa canina (L)                               14.7 [+ or -] 1.0
Prunus sogdiana (Fr)                          17.0 [+ or -] 0.15
Chenopodium album (Fr)                        18.3 [+ or -] 0.71 *
Rubus caesius (L)                             19.2 [+ or -] 0.12 *
Chenopodium album (R)                         14.3 [+ or -] 0.45
Amaranthus retroplexus (L)                    13.3 [+ or -] 0.6
Prunus sogdiana (L)                           18.1 [+ or -] 0.92 *
Amaranthus retroplexus (St)                   17.0 [+ or -] 0.71
Amaranthus retroplexus (Fr)                   14.3 [+ or -] 0.19
Prunus sogdiana (Sk)                          15.3 [+ or -] 0.21
Prunus sogdiana (R)                           18.0 [+ or -] 1.3 *
Prunus sogdiana (O)                           17.0 [+ or -] 0.43
Pheum Fedtshenokovi (F)                       13.2 [+ or -] 0.47
Atraphaxis pyrifolia (Sk)                     15.0 [+ or -] 0.53
Atraphaxis pyrifolia (St)                     13.7 [+ or -] 0.79
Atraphaxis pyrifolia (R)                      17.2 [+ or -] 0.42
Amygdalis spinosissima (S)                    12.3 [+ or -] 0.24
Cerasus erythrocapra (L)                      14.2 [+ or -] 0.73
Avena sativa (S)                              17.0 [+ or -] 0.15
Amygdalis bucharica (L)                       13.7 [+ or -] 0.79
Trifolium pratense (F)                        19.2 [+ or -] 0.71 *
Amygdalis bucharica (Sk)                      14.2 [+ or -] 0.48
Pheum Fedtshenokovi (L)                       17.9 [+ or -] 1.24
Amygdalis bucharica (L)                       15.0 [+ or -] 0.15
Trifolium repens (O)                          18.4 [+ or -] 0.13
Solidago dahurica Kitag (O)                   12.3 [+ or -] 0.72
Acroptilon repens (L)Op.(O)                   17.2 [+ or -] 0.49
Melandrium turkestanicus (Rgl)Vved (R)        12.3 [+ or -] 0.73
Inula helenium (R)                            15.0 [+ or -] 0.28
Artemisia vulgaris h. (O)                     16.3 [+ or -] 0.39
Berberis integerrima (Bge) (Fr)               14.4 [+ or -] 0.47
Juniperus turkestanica Kom (L)                17.2 [+ or -] 0.78
Solonum nigra h. (Fr)                         15.0 [+ or -] 0.43
Solidago dahurica kitag (O)                   12.3 [+ or -] 0.47
Melandrium turkestanicus (Rgl)Vved (O)        17.4 [+ or -] 0.78
Acroptilon repens (F)                         13.9 [+ or -] 0.49
Trifolim pratense h.(F)                       14.2 [+ or -] 0.17
Cousinia saawertziwii Regel (O)               15.3 [+ or -] 0.79
Anaphalis Velutina Krasch (O)                 17.3 [+ or -] 0.48
Astragalus sp. (O)                            14.3 [+ or -] 0.48
Berberis oblonga (Rgl) Schneid [R]            14.7 [+ or -] 0.79
Hieracium procerum Fr [R]                     12.3 [+ or -] 0.47
Stachys betoniciflora rupr. [R]               17. 3 [+ or -] 0.13
Acantholimon erythraeum Bge (A)               18.4 [+ or -] 0.49 *
Pulicaria salviifolia Bunge (R)               18.2 [+ or -] 0.74 *
Psoralea drupacea Bunge (S)                   20.5 [+ or -] 0.95 *
Trifolim pratense h.(O)                       14.2 [+ or -] 0.24
Melandrium turkestanicus (Rgl)Vved (Fr)       12.3 [+ or -] 0.71
Artemisia vulgaris h. (R)                     11.7 [+ or -] 0.83
Descurania Sophia (L) Schur (Fr)              17.3 [+ or -] 0.49
Xantium strumarium h. (St)                    12.9 [+ or -] 0.55
Conum maculatum h. (St)                       11.8 [+ or -] 0.67
Cortusa turkestanica A.Los (O)                16.2 [+ or -] 0.79
Tanasetopsis mucronatun S kovalev (O)         17.8 [+ or -] 0.97
Xantium strumarium h. (S)                     13.2 [+ or -] 0.42
Herniaria glabra h. (O)                       10.0 [+ or -] 0.85
Leonurus turkestanicusV.Krecr et Kupr (O)     11.2 [+ or -] 1.35
Arctium tomentisum Mill (R)                   12.1 [+ or -] 0.67
Ziziphora pedicillate Parii et Vved (R)       19.7 [+ or -] 1.43
Solidago dahurica Kitag (F)                   14.7 [+ or -] 0.81
Hierasiun procerum Fr (O)                     15.6 [+ or -] 0.67
Solonum nigra h. (St)                         12.6 [+ or -] 0.24
Agrimonia asiatica lus (R)                    13.6 [+ or -] 0.42
Xantium strumarium h.(R)                      14.7 [+ or -] 0.81
Cortusa turkestanica A. Los (F)               11.8 [+ or -] 0.3
Artemisia vilgaris L.(F)                      17.3 [+ or -] 0.67
Chamenerium angustibolium (L) Scop (R)        18.3 [+ or -] 0.95
Stachyopsys oblongata M. Popet Vved (O)       12.4 [+ or -] 0.79
Stachys betoniciflora Rupr (F)                17.1 [+ or -] 1.24
Ziziphora pedicillate Parii et Vved (St)      18.9 [+ or -] 0.29 *
Spiraea pilosa Franch (O)                     17.0 [+ or -] 1.23
Acroptilon repens (R)                         18.4 [+ or -] 0.45 *
Solonum nigra h. (R)                          12.5 [+ or -] 0.17
Phragmites communis Trin (St)                 17.6 [+ or -] 0.79
Cortusa turkestanica A. hos (R)               18.8 [+ or -] 0.97 *
Trigonella pamirica Boriss (A)                13.4 [+ or -] 0.48
Astragalus sp. (R)                            15.5 [+ or -] 0.57
Trifolium pratense L. (R)                     18.7 [+ or -] 0.49 *
Solonum nigra h. (L)                          14.3 [+ or -] 0.74
Pulicaria salviibolia Binge (St)              14.7 [+ or -] 0.85
Phragmites communis Tren (L)                  16.3 [+ or -] 0.23
Phragmites communis Trin (R)                  12.4 [+ or -] 0.43
Oberna beechen (L) Ikonn (Fr)                 12.4 [+ or -] 0.75
Agrimonia ariatica lus (L)                    18.3 [+ or -] 0.13 *
Serophularia umbrosa Dumort (St)              11.9 [+ or -] 0.47
Serophularia umbrosa Dumort (O)               10.9 [+ or -] 0.49
Siderities montana L (St)                     18.0 [+ or -] 0.12 *
Phlomis olgae Rgl (R)                         17.1 [+ or -] 0.18
Serratula alatavica c.A.M. (F)                16.3 [+ or -] 0.94
Serratula alatavica c.A.M.(O)                 12.4 [+ or -] 0.17
Inula helenium L (F)                          13.1 [+ or -] 0.74
Psoralea drupacea Bunge (R)                   12.4 [+ or -] 0.19
Inula helenium L (L)                          17.3 [+ or -] 0.89
Phlomis sewerzowii Rgl (O)                    16.6 [+ or -] 0.62

Note: F--flower; R- root; S--seed; FR--fruit; L--leaves; St--stem;
O--overground part; Sk--skin; E--entire plant; I--inflorescence;
A--upper part of overground part. Authentic difference P<0,05:
*--from intact group; **--from controlled group.

TABLE 3. THE SCREENING OF VEGETABLE EXTRACTS ON PRESENCE OF
HYPOLIPIDEMIC EFFECT UNDER ETHANOL HYPERLIPIDEMIA

Name of Extracts                                  OChS, mmol/l
1                                                      2

Intact group                                 0.99 [+ or -] 0.07
Controlled group                             1.74 [+ or -] 0.1
Plantago lanceolata [R]                      1.96 [+ or -] 0.28 *
Rosa canina (Sk)                             1.85 [+ or -] 0.11 *
Cratalgus songarica [R]                      1.75 [+ or -] 0.05 *
Cynodon dactulon [R]                         1.83 [+ or -] 0.16 *
Prunus sogdiana [R]                          1.72 [+ or -] 0.15 *
Rosa canina [R]                              1.91 [+ or -] 0.11 *
Crataegus pontica (L)                        1.78 [+ or -] 0.15 *
luniperus zeravshanica (Fr)                  1.55 [+ or -] 0.2 *
Cynodon dactulon (O)                         1.69 [+ or -] 0.15 *
Rosa canina (Fr)                              1.8 [+ or -] 0.03 *
Picnomon acarna (O)                          1.65 [+ or -] 0.12 *
Alhagi pseudalhagi [R]                       1.84 [+ or -] 0.1 *
Rosa canina (L)                              1.96 [+ or -] 0.2 *
Prunus sogdiana (Fr)                         1.78 [+ or -] 0.2 *
Chenopodium album (Fr)                       1.84 [+ or -] 0.1 *
Rubus caesius (L)                            1.69 [+ or -] 0.2 *
Chenopodium album (R)                        1.91 [+ or -] 0.1 *
Amaranthus retroplexus (L)                   1.75 [+ or -] 0.1 *
Prunus sogdiana (L)                          1.66 [+ or -] 0.04 *
Amaranthus retroplexus (St)                  1.38 [+ or -] 0.17 *
Amaranthus retroplexus (Fr)                  1.89 [+ or -] 0.1 *
Prunus sogdiana (Sk)                          1.8 [+ or -] 0.2 *
Prunus sogdiana (R)                          1.79 [+ or -] 0.2 *
Prunus sogdiana (O)                          1.69 [+ or -] 0.15 *
Pheum Fedtshenokovi (F)                      1.55 [+ or -] 0.3 *
Atraphaxis pyrifolia (Sk)                    1.63 [+ or -] 0.2 *
Atraphaxis pyrifolia (St)                    1.89 [+ or -] 0.1 *
Atraphaxis pyrifolia (R)                     1.73 [+ or -] 0.1 *
Amygdalis spinosissima (S)                    1.9 [+ or -] 0.2 *
Cerasus erythrocapra (L)                      1.8 [+ or -] 0.01 *
Avena sativa (S)                             0.87 [+ or -] 0.089 **
Amygdalis bucharica (L)                      1.75 [+ or -] 0.1 *
Trifolium pratense (F)                       1.68 [+ or -] 0.2 *
Amygdalis bucharica (Sk)                     1.83 [+ or -] 0.1 *
Pheum Fedtshenokovi (L)                      1.91 [+ or -] 0.1 *
Amygdalis bucharica (L)                       1.7 [+ or -] 0.1 *
Trifolium repens (O)                         1.79 [+ or -] 0.2 *
Solidago dahurica Kitag (O)                   1.9 [+ or -] 0.11 *
Acroptilon repens (L)Op.(O)                  1.84 [+ or -] 0.16 *
Melandrium turkestanicus (Rgl)Vved (R)        1.9 [+ or -] 0.04 *
Inula helenium (R)                           1.78 [+ or -] 0.15 *
Artemisia vulgaris h. (O)                    1.95 [+ or -] 0.11 *
Berberis integerrima (Bge) (Fr)              1.74 [+ or -] 0.12 *
Juniperus turkestanica Kom (L)               1.48 [+ or -] 0.06 *
Solonum nigra h. (Fr)                        1.75 [+ or -] 0.05 *
Solidago dahurica kitag [R]                  1.96 [+ or -] 0.28 *
Melandrium turkestanicus (Rgl)Vved (O)       1.95 [+ or -] 0.11 *
Acroptilon repens (F)                        1.86 [+ or -] 0.12 *
Trifolim pratense h.(F)                      1.72 [+ or -] 0.1 *
Cousinia saawertziwii Regel (O)              1.63 [+ or -] 0.38 *
Anaphalis Velutina Krasch (O)                1.65 [+ or -] 0.18 *
Astragalus sp. (O)                           1.73 [+ or -] 0.1 *
Berberis oblonga (Rgl) Schneid [R]           1.87 [+ or -] 0.03 *
Hieracium procerum Fr [R]                     2.0 [+ or -] 0.2 *
Stachys betoniciflora rupr. [R]               1.9 [+ or -] 0.06 *
Acantholimon erythraeum Bge (A)              1.73 [+ or -] 0.12 *
Pulicaria salviifolia Bunge (R)              1.73 [+ or -] 0.1 *
Psoralea drupacea Bunge (S)                   1.7 [+ or -] 0.1 *
Trifolim pratense h.(O)                      1.85 [+ or -] 0.1 *
Melandrium turkestanicus (Rgl)Vved (Fr)      1.75 [+ or -] 0.1 *
Artemisia vulgaris h. (R)                    1.87 [+ or -] 0.1 *
Descurania Sophia (L) Schur (Fr)             1.76 [+ or -] 0.27 *
Xantium strumarium h. (St)                   1.78 [+ or -] 0.2 *
Conum maculatum h. (St)                      1.75 [+ or -] 0.1 *
Cortusa turkestanica A.Los (O)               1.67 [+ or -] 0.05 *
Tanasetopsis mucronatun S kovalev (O)        1.65 [+ or -] 0.07 *
Xantium strumarium h. (S)                    1.47 [+ or -] 0.32 *
Herniaria glabra h. (O)                      1.45 [+ or -] 0.31 *
Leonurus turkestanicusV.Krecr et Kupr (O)    1.46 [+ or -] 0.18 *
Arctium tomentisum Mill (R)                  1.54 [+ or -] 0.2 *
Ziziphora pedicillate Parii et Vved (R)      1.86 [+ or -] 0.03
Solidago dahurica Kitag (F)                  1.72 [+ or -] 0.15 *
Hierasiun procerum Fr (O)                    1.76 [+ or -] 0.05 *
Solonum nigra h. (St)                        1.68 [+ or -] 0.22 *
Agrimonia asiatica lus (R)                    1.5 [+ or -] 0.16 *
Xantium strumarium h.(R)                     1.85 [+ or -] 0.11 *
Cortusa turkestanica A. Los (F)              1.68 [+ or -] 0.23 *
Artemisia vilgaris L.(F)                     1.83 [+ or -] 0.18 *
Chamenerium angustibolium (L) Scop (R)       1.63 [+ or -] 0.35 *
Stachyopsys oblongata M. Popet Vved (O)      1.73 [+ or -] 0.15 *
Stachys betoniciflora Rupr (F)               1.85 [+ or -] 1.33 *
Ziziphora pedicillate Parii et Vved (St)     1.92 [+ or -] 0.09 *
Spiraea pilosa Franch (O)                    1.73 [+ or -] 0.16 *
Acroptilon repens (R)                        1.94 [+ or -] 0.1 *
Solonum nigra h. (R)                         1.91 [+ or -] 0.02 *
Phragmites communis Trin (St)                1.62 [+ or -] 0.21 *
Cortusa turkestanica A. hos (R)              1.53 [+ or -] 0.31 *
Trigonella pamirica Boriss (A)               1.58 [+ or -] 0.01 *
Astragalus sp. (R)                           1.62 [+ or -] 0.21 *
Trifolium pratense L. (R)                    1.78 [+ or -] 0.087 *
Solonum nigra h. (L)                         1.85 [+ or -] 0.13 *
Pulicaria salviibolia Binge (St)             1.75 [+ or -] 0.05 *
Phragmites communis Tren (L)                 1.77 [+ or -] 0.17 *
Phragmites communis Trin (R)                 1.76 [+ or -] 0.7 *
Oberna beechen (L) Ikonn (Fr)                1.81 [+ or -] 0.22 *
Agrimonia ariatica Ius (L)                   1.74 [+ or -] 0.12 *
Serophularia umbrosa Dumort (St)             1.78 [+ or -] 0.17 *
Serophularia umbrosa Dumort (O)              1.92 [+ or -] 0.17 *
Siderities montana L (St)                    1.85 [+ or -] 0.13 *
Phlomis olgae Rgl (R)                        1.86 [+ or -] 0.05 *
Serratula alatavica c.A.M. (F)               1.89 [+ or -] 0.14 *
Serratula alatavica c.A.M.(O)                1.81 [+ or -] 0.12 *
Inula helenium L (F)                         1.91 [+ or -] 0.24 *
Psoralea drupacea Bunge (R)                  1.86 [+ or -] 0.16 *
Inula helenium L (L)                         1.89 [+ or -] 0.09 *
Phlomis sewerzowii Rgl (O)                    1.8 [+ or -] 0.35 *

Name of Extracts                                  TG, mmol/l
1                                                      3

Intact group                                 0.68 [+ or -] 0.09
Controlled group                             1.17 [+ or -] 0.16
Plantago lanceolata [R]                      0.94 [+ or -] 0.1 *
Rosa canina (Sk)                             0.92 [+ or -] 0.09 *
Cratalgus songarica [R]                      1.07 [+ or -] 0.02 *
Cynodon dactulon [R]                         0.89 [+ or -] 0.07
Prunus sogdiana [R]                          0.98 [+ or -] 0.11 *
Rosa canina [R]                               0.9 [+ or -] 0.06 *
Crataegus pontica (L)                        1.04 [+ or -] 0.04 *
luniperus zeravshanica (Fr)                  1.07 [+ or -] 0.19 *
Cynodon dactulon (O)                         0.94 [+ or -] 0.09 *
Rosa canina (Fr)                             0.94 [+ or -] 0.1 *
Picnomon acarna (O)                          1.03 [+ or -] 0.2 *
Alhagi pseudalhagi [R]                       0.97 [+ or -] 0.1 *
Rosa canina (L)                              0.95 [+ or -] 0.1 *
Prunus sogdiana (Fr)                         0.96 [+ or -] 0.2 *
Chenopodium album (Fr)                       0.98 [+ or -] 0.2 *
Rubus caesius (L)                            0.96 [+ or -] 0.1 *
Chenopodium album (R)                        0.98 [+ or -] 0.15 *
Amaranthus retroplexus (L)                   0.78 [+ or -] 0.1
Prunus sogdiana (L)                          0.98 [+ or -] 0.1 *
Amaranthus retroplexus (St)                  0.85 [+ or -] 0.2
Amaranthus retroplexus (Fr)                  0.94 [+ or -] 0.1 *
Prunus sogdiana (Sk)                         0.98 [+ or -] 0.1 *
Prunus sogdiana (R)                          1.07 [+ or -] 0.1 *
Prunus sogdiana (O)                          1.02 [+ or -] 0.1 *
Pheum Fedtshenokovi (F)                      0.86 [+ or -] 0.075
Atraphaxis pyrifolia (Sk)                     1.0 [+ or -] 0.1 *
Atraphaxis pyrifolia (St)                    1.04 [+ or -] 0.1 *
Atraphaxis pyrifolia (R)                     0.99 [+ or -] 0.15 *
Amygdalis spinosissima (S)                   1.04 [+ or -] 0.1 *
Cerasus erythrocapra (L)                     1.13 [+ or -] 0.2 *
Avena sativa (S)                             0.67 [+ or -] 0.05 **
Amygdalis bucharica (L)                      1.35 [+ or -] 0.22 *
Trifolium pratense (F)                       1.13 [+ or -] 0.006 *
Amygdalis bucharica (Sk)                     1.02 [+ or -] 0.12 *
Pheum Fedtshenokovi (L)                       0.8 [+ or -] 0.07
Amygdalis bucharica (L)                      1.12 [+ or -] 0.06 *
Trifolium repens (O)                         0.93 [+ or -] 0.12 *
Solidago dahurica Kitag (O)                  1.05 [+ or -] 0.2 *
Acroptilon repens (L)Op.(O)                  1.12 [+ or -] 0.1 *
Melandrium turkestanicus (Rgl)Vved (R)       0.79 [+ or -] 0.17
Inula helenium (R)                            1.0 [+ or -] 0.2 *
Artemisia vulgaris h. (O)                    1.02 [+ or -] 0.1 *
Berberis integerrima (Bge) (Fr)              0.96 [+ or -] 0.2 *
Juniperus turkestanica Kom (L)               0.97 [+ or -] 0.1 *
Solonum nigra h. (Fr)                        0.91 [+ or -] 0.06 *
Solidago dahurica kitag [R]                  0.89 [+ or -] 0.1 *
Melandrium turkestanicus (Rgl)Vved (O)       0.84 [+ or -] 0.06 *
Acroptilon repens (F)                        0.91 [+ or -] 0.1 *
Trifolim pratense h.(F)                      0.98 [+ or -] 0.1 *
Cousinia saawertziwii Regel (O)              0.93 [+ or -] 0.1 *
Anaphalis Velutina Krasch (O)                0.91 [+ or -] 0.1 *
Astragalus sp. (O)                           1.07 [+ or -] 0.067 *
Berberis oblonga (Rgl) Schneid [R]           0.98 [+ or -] 0.1 *
Hieracium procerum Fr (R)                     0.9 [+ or -] 0.087 *
Stachys betoniciflora rupr. [R]              0.97 [+ or -] 0.14 *
Acantholimon erythraeum Bge (A)               1.1 [+ or -] 0.01 *
Pulicaria salviifolia Bunge (R)              1.02 [+ or -] 0.12 *
Psoralea drupacea Bunge (S)                  1.01 [+ or -] 0.09 *
Trifolim pratense h.(O)                      0.84 [+ or -] 0.14
Melandrium turkestanicus (Rgl)Vved (Fr)       1.0 [+ or -] 0.11 *
Artemisia vulgaris h. (R)                    1.03 [+ or -] 0.13 *
Descurania Sophia (L) Schur (Fr)              1.1 [+ or -] 0.16 *
Xantium strumarium h. (St)                   1.08 [+ or -] 0.27 *
Conum maculatum h. (St)                      1.03 [+ or -] 0.078 *
Cortusa turkestanica A.Los (O)                0.9 [+ or -] 0.082 *
Tanasetopsis mucronatun S kovalev (O)        0.96 [+ or -] 0.09 *
Xantium strumarium h. (S)                    0.95 [+ or -] 0.04 *
Herniaria glabra h. (O)                      0.81 [+ or -] 0.86 *
Leonurus turkestanicusV.Krecr et Kupr (O)    0.95 [+ or -] 0.044 *
Arctium tomentisum Mill (R)                  0.96 [+ or -] 0.044 *
Ziziphora pedicillate Parii et Vved (R)      0.95 [+ or -] 0.11 *
Solidago dahurica Kitag (F)                  0.95 [+ or -] 0.05 *
Hierasiun procerum Fr (O)                     1.0 [+ or -] 0.12 *
Solonum nigra h. (St)                        0.88 [+ or -] 0.044
Agrimonia asiatica lus (R)                   1.02 [+ or -] 0.06 *
Xantium strumarium h.(R)                     0.97 [+ or -] 0.08 *
Cortusa turkestanica A. Los (F)              1.01 [+ or -] 0.08 *
Artemisia vilgaris L.(F)                     0.98 [+ or -] 0.11 *
Chamenerium angustibolium (L) Scop (R)       1.04 [+ or -] 0.07 *
Stachyopsys oblongata M. Popet Vved (O)      1.04 [+ or -] 0.15 *
Stachys betoniciflora Rupr (F)               0.96 [+ or -] 0.057 *
Ziziphora pedicillate Parii et Vved (St)     0.93 [+ or -] 0.1 *
Spiraea pilosa Franch (O)                    0.98 [+ or -] 0.052 *
Acroptilon repens (R)                        0.97 [+ or -] 0.071 *
Solonum nigra h. (R)                         1.01 [+ or -] 0.051 *
Phragmites communis Trin (St)                 1.0 [+ or -] 0.094 *
Cortusa turkestanica A. hos (R)               1.1 [+ or -] 0.053 *
Trigonella pamirica Boriss (A)               0.96 [+ or -] 0.054 *
Astragalus sp. (R)                           0.96 [+ or -] 0.14 *
Trifolium pratense L. (R)                    0.93 [+ or -] 0.039 *
Solonum nigra h. (L)                         1.13 [+ or -] 0.038 *
Pulicaria salviibolia Binge (St)             1.02 [+ or -] 0.1 *
Phragmites communis Tren (L)                 1.01 [+ or -] 0.082 *
Phragmites communis Trin (R)                 1.03 [+ or -] 0.2 *
Oberna beechen (L) Ikonn (Fr)                1.18 [+ or -] 0.15 *
Agrimonia ariatica Ius (L)                    0.9 [+ or -] 0.1 *
Serophularia umbrosa Dumort (St)             1.05 [+ or -] 0.13
Serophularia umbrosa Dumort (O)              0.98 [+ or -] 0.34 *
Siderities montana L (St)                    0.85 [+ or -] 0.05
Phlomis olgae Rgl (R)                        1.11 [+ or -] 0.09 *
Serratula alatavica c.A.M. (F)               0.99 [+ or -] 0.1 *
Serratula alatavica c.A.M.(O)                0.89 [+ or -] 0.1
Inula helenium L (F)                         0.77 [+ or -] 0.1
Psoralea drupacea Bunge (R)                  1.01 [+ or -] 0.1 *
Inula helenium L (L)                         0.92 [+ or -] 0.14 *
Phlomis sewerzowii Rgl (O)                   0.97 [+ or -] 0.06 *

Name of Extracts                                ChS HDL, mmol/l
1                                                      4

Intact group                                 0.46 [+ or -] 0.9
Controlled group                             0.28 [+ or -] 0.04
Plantago lanceolata [R]                      0.28 [+ or -] 0.02 *
Rosa canina (Sk)                             0.23 [+ or -] 0.03 *
Cratalgus songarica [R]                      0.28 [+ or -] 0.02 *
Cynodon dactulon [R]                         0.29 [+ or -] 0.02 *
Prunus sogdiana [R]                          0.25 [+ or -] 0.04 *
Rosa canina [R]                              0.27 [+ or -] 0.04 *
Crataegus pontica (L)                        0.25 [+ or -] 0.03 *
luniperus zeravshanica (Fr)                  0.26 [+ or -] 0.04 *
Cynodon dactulon (O)                         0.24 [+ or -] 0.03 *
Rosa canina (Fr)                             0.19 [+ or -] 0.04 *
Picnomon acarna (O)                           0.2 [+ or -] 0.03 *
Alhagi pseudalhagi [R]                       0.26 [+ or -] 0.02 *
Rosa canina (L)                              0.32 [+ or -] 0.05
Prunus sogdiana (Fr)                         0.24 [+ or -] 0.07 *
Chenopodium album (Fr)                       0.26 [+ or -] 0.06 *
Rubus caesius (L)                            0.25 [+ or -] 0.09 *
Chenopodium album (R)                        0.32 [+ or -] 0.1
Amaranthus retroplexus (L)                   0.24 [+ or -] 0.06
Prunus sogdiana (L)                          0.29 [+ or -] 0.08 *
Amaranthus retroplexus (St)                  0.25 [+ or -] 0.06 *
Amaranthus retroplexus (Fr)                  0.28 [+ or -] 0.05 *
Prunus sogdiana (Sk)                          0.2 [+ or -] 0.02 *
Prunus sogdiana (R)                          0.34 [+ or -] 0.06
Prunus sogdiana (O)                          0.33 [+ or -] 0.06
Pheum Fedtshenokovi (F)                       0.2 [+ or -] 0.05
Atraphaxis pyrifolia (Sk)                     0.3 [+ or -] 0.04
Atraphaxis pyrifolia (St)                    0.24 [+ or -] 0.08 *
Atraphaxis pyrifolia (R)                     0.29 [+ or -] 0.08 *
Amygdalis spinosissima (S)                    0.3 [+ or -] 0.04
Cerasus erythrocapra (L)                     0.25 [+ or -] 0.09 *
Avena sativa (S)                             0.43 [+ or -] 0.02 **
Amygdalis bucharica (L)                       0.3 [+ or -] 0.1
Trifolium pratense (F)                       0.25 [+ or -] 0.026 *
Amygdalis bucharica (Sk)                     0.27 [+ or -] 0.062 *
Pheum Fedtshenokovi (L)                      0.24 [+ or -] 0.01 *
Amygdalis bucharica (L)                      0.21 [+ or -] 0.04 *
Trifolium repens (O)                          0.2 [+ or -] 0.05 *
Solidago dahurica Kitag (O)                  0.19 [+ or -] 0.01 *
Acroptilon repens (L)Op.(O)                  0.22 [+ or -] 0.034 *
Melandrium turkestanicus (Rgl)Vved (R)        0.2 [+ or -] 0.029 *
Inula helenium (R)                           0.28 [+ or -] 0.06 *
Artemisia vulgaris h. (O)                    0.24 [+ or -] 0.06 *
Berberis integerrima (Bge) (Fr)              0.17 [+ or -] 0.04 *
Juniperus turkestanica Kom (L)               0.27 [+ or -] 0.02 *
Solonum nigra h. (Fr)                        0.37 [+ or -] 0.04
Solidago dahurica kitag [R]                  0.19 [+ or -] 0.02 *
Melandrium turkestanicus (Rgl)Vved (O)       0.28 [+ or -] 0.06 *
Acroptilon repens (F)                        0.27 [+ or -] 0.03 *
Trifolim pratense h.(F)                      0.26 [+ or -] 0.077 *
Cousinia saawertziwii Regel (O)              0.23 [+ or -] 0.022 *
Anaphalis Velutina Krasch (O)                0.28 [+ or -] 0.035 *
Astragalus sp. (O)                           0.19 [+ or -] 0.016 *
Berberis oblonga (Rgl) Schneid [R]           0.29 [+ or -] 0.032 *
Hieracium procerum Fr [R]                    0.27 [+ or -] 0.078 *
Stachys betoniciflora rupr. [R]              0.28 [+ or -] 0.022 *
Acantholimon erythraeum Bge (A)              0.28 [+ or -] 0.04 *
Pulicaria salviifolia Bunge (R)              0.31 [+ or -] 0.04
Psoralea drupacea Bunge (S)                  0.18 [+ or -] 0.026 *
Trifolim pratense h.(O)                      0.25 [+ or -] 0.034 *
Melandrium turkestanicus (Rgl)Vved (Fr)      0.31 [+ or -] 0.07 *
Artemisia vulgaris h. (R)                    0.27 [+ or -] 0.035 *
Descurania Sophia (L) Schur (Fr)             0.25 [+ or -] 0.026 *
Xantium strumarium h. (St)                   0.23 [+ or -] 0.026 *
Conum maculatum h. (St)                      0.21 [+ or -] 0.03 *
Cortusa turkestanica A.Los (O)               0.27 [+ or -] 0.067 *
Tanasetopsis mucronatun S kovalev (O)         0.3 [+ or -] 0.075
Xantium strumarium h. (S)                    0.24 [+ or -] 0.038 *
Herniaria glabra h. (O)                      0.21 [+ or -] 0.012 *
Leonurus turkestanicusV.Krecr et Kupr (O)    0.26 [+ or -] 0.044 *
Arctium tomentisum Mill (R)                   0.3 [+ or -] 0.085
Ziziphora pedicillate Parii et Vved (R)      0.24 [+ or -] 0.045 *
Solidago dahurica Kitag (F)                  0.32 [+ or -] 0.071
Hierasiun procerum Fr (O)                    0.34 [+ or -] 0.043
Solonum nigra h. (St)                         0.3 [+ or -] 0.018
Agrimonia asiatica lus (R)                   0.23 [+ or -] 0.035 *
Xantium strumarium h.(R)                      0.3 [+ or -] 0.09
Cortusa turkestanica A. Los (F)              0.32 [+ or -] 0.07
Artemisia vilgaris L.(F)                     0.23 [+ or -] 0.03 *
Chamenerium angustibolium (L) Scop (R)        0.3 [+ or -] 0.041
Stachyopsys oblongata M. Popet Vved (O)      0.26 [+ or -] 0.056 *
Stachys betoniciflora Rupr (F)                0.3 [+ or -] 0.075
Ziziphora pedicillate Parii et Vved (St)     0.23 [+ or -] 0.018 *
Spiraea pilosa Franch (O)                    0.19 [+ or -] 0.018 *
Acroptilon repens (R)                        0.28 [+ or -] 0.04 *
Solonum nigra h. (R)                         0.32 [+ or -] 0.11
Phragmites communis Trin (St)                 0.3 [+ or -] 0.024
Cortusa turkestanica A. hos (R)              0.21 [+ or -] 0.057 *
Trigonella pamirica Boriss (A)               0.24 [+ or -] 0.075 *
Astragalus sp. (R)                           0.31 [+ or -] 0.029
Trifolium pratense L. (R)                    0.23 [+ or -] 0.058 *
Solonum nigra h. (L)                         0.21 [+ or -] 0.015 *
Pulicaria salviibolia Binge (St)             0.27 [+ or -] 0.067 *
Phragmites communis Tren (L)                 0.16 [+ or -] 0.015 *
Phragmites communis Trin (R)                 0.31 [+ or -] 0.1
Oberna beechen (L) Ikonn (Fr)                0.32 [+ or -] 0.02
Agrimonia ariatica Ius (L)                   0.31 [+ or -] 0.1
Serophularia umbrosa Dumort (St)              0.3 [+ or -] 0.04
Serophularia umbrosa Dumort (O)               0.3 [+ or -] 0.07
Siderities montana L (St)                    0.25 [+ or -] 0.04 *
Phlomis olgae Rgl (R)                        0.36 [+ or -] 0.035
Serratula alatavica c.A.M. (F)                0.3 [+ or -] 0.03 *
Serratula alatavica c.A.M.(O)                0.23 [+ or -] 0.04 *
Inula helenium L (F)                         0.28 [+ or -] 0.01 *
Psoralea drupacea Bunge (R)                  0.25 [+ or -] 0.04 *
Inula helenium L (L)                         0.29 [+ or -] 0.05 *
Phlomis sewerzowii Rgl (O)                    0.3 [+ or -] 0.08

Name of Extracts                                    OL, g/l
1                                                      5

Intact group                                 4.21 [+ or -] 0.36
Controlled group                              6.3 [+ or -] 0.43
Plantago lanceolata [R]                     10.47 [+ or -] 0.86 *
Rosa canina (Sk)                             6.94 [+ or -] 1.17 *
Cratalgus songarica [R]                      8.26 [+ or -] 0.5 *
Cynodon dactulon [R]                          8.9 [+ or -] 1.59 *
Prunus sogdiana [R]                          7.22 [+ or -] 0.57 *
Rosa canina [R]                               7.4 [+ or -] 0.49 *
Crataegus pontica (L)                         8.4 [+ or -] 1.74 *
luniperus zeravshanica (Fr)                 12.37 [+ or -] 3.48 *
Cynodon dactulon (O)                         7.84 [+ or -] 0.52 *
Rosa canina (Fr)                             5.97 [+ or -] 1.03
Picnomon acarna (O)                           5.7 [+ or -] 0.89
Alhagi pseudalhagi [R]                        7.8 [+ or -] 0.25 *
Rosa canina (L)                              7.01 [+ or -] 0.92 *
Prunus sogdiana (Fr)                         5.77 [+ or -] 0.41
Chenopodium album (Fr)                       5.94 [+ or -] 0.74
Rubus caesius (L)                            6.18 [+ or -] 0.87 *
Chenopodium album (R)                        7.13 [+ or -] 0.24 *
Amaranthus retroplexus (L)                   5.36 [+ or -] 0.85
Prunus sogdiana (L)                          6.01 [+ or -] 0.55 *
Amaranthus retroplexus (St)                  6.29 [+ or -] 1.1 *
Amaranthus retroplexus (Fr)                  7.33 [+ or -] 0.2 *
Prunus sogdiana (Sk)                         7.34 [+ or -] 0.6 *
Prunus sogdiana (R)                          7.06 [+ or -] 0.69 *
Prunus sogdiana (O)                           9.0 [+ or -] 0.23 *
Pheum Fedtshenokovi (F)                       9.6 [+ or -] 0.57 *
Atraphaxis pyrifolia (Sk)                     9.9 [+ or -] 1.13 *
Atraphaxis pyrifolia (St)                     8.4 [+ or -] 1.69 *
Atraphaxis pyrifolia (R)                     10.1 [+ or -] 0.67 *
Amygdalis spinosissima (S)                   10.3 [+ or -] 0.38 *
Cerasus erythrocapra (L)                      9.4 [+ or -] 0.91 *
Avena sativa (S)                              4.1 [+ or -] 0.13 **
Amygdalis bucharica (L)                       7.9 [+ or -] 1.2 *
Trifolium pratense (F)                        9.6 [+ or -] 0.46 *
Amygdalis bucharica (Sk)                      9.9 [+ or -] 1.2 *
Pheum Fedtshenokovi (L)                       9.3 [+ or -] 0.43 *
Amygdalis bucharica (L)                      10.6 [+ or -] 0.55 *
Trifolium repens (O)                          8.4 [+ or -] 1.17 *
Solidago dahurica Kitag (O)                  10.8 [+ or -] 1.29 *
Acroptilon repens (L)Op.(O)                  10.5 [+ or -] 0.89 *
Melandrium turkestanicus (Rgl)Vved (R)       10.1 [+ or -] 1.74 *
Inula helenium (R)                           11.1 [+ or -] 0.63 *
Artemisia vulgaris h. (O)                    10.4 [+ or -] 0.44 *
Berberis integerrima (Bge) (Fr)               9.5 [+ or -] 1.39 *
Juniperus turkestanica Kom (L)               5.63 [+ or -] 0.3
Solonum nigra h. (Fr)                        10.4 [+ or -] 1.01 *
Solidago dahurica kitag [R]                  10.6 [+ or -] 0.61 *
Melandrium turkestanicus (Rgl)Vved (O)       11.0 [+ or -] 1.21 *
Acroptilon repens (F)                         9.1 [+ or -] 1.19 *
Trifolim pratense h.(F)                      10.5 [+ or -] 1.26 *
Cousinia saawertziwii Regel (O)               8.9 [+ or -] 0.2 *
Anaphalis Velutina Krasch (O)                 9.9 [+ or -] 0.69 *
Astragalus sp. (O)                            8.6 [+ or -] 0.62 *
Berberis oblonga (Rgl) Schneid [R]            8.7 [+ or -] 1.59 *
Hieracium procerum Fr [R]                     9.7 [+ or -] 1.29 *
Stachys betoniciflora rupr. [R]               7.9 [+ or -] 0.56 *
Acantholimon erythraeum Bge (A)               6.1 [+ or -] 0.4 *
Pulicaria salviifolia Bunge (R)               9.2 [+ or -] 1.15 *
Psoralea drupacea Bunge (S)                   7.4 [+ or -] 0.49 *
Trifolim pratense h.(O)                      10.5 [+ or -] 0.49 *
Melandrium turkestanicus (Rgl)Vved (Fr)      10.6 [+ or -] 0.48 *
Artemisia vulgaris h. (R)                    10.2 [+ or -] 1.14 *
Descurania Sophia (L) Schur (Fr)              6.4 [+ or -] 0.65 *
Xantium strumarium h. (St)                    8.9 [+ or -] 0.62 *
Conum maculatum h. (St)                       9.9 [+ or -] 0.46 *
Cortusa turkestanica A.Los (O)               10.8 [+ or -] 0.68 *
Tanasetopsis mucronatun S kovalev (O)         7.1 [+ or -] 0.53 *
Xantium strumarium h. (S)                     7.6 [+ or -] 0.53 *
Herniaria glabra h. (O)                       7.8 [+ or -] 0.84 *
Leonurus turkestanicusV.Krecr et Kupr (O)     8.6 [+ or -] 0.82 *
Arctium tomentisum Mill (R)                   7.7 [+ or -] 0.73 *
Ziziphora pedicillate Parii et Vved (R)       7.9 [+ or -] 0.55 *
Solidago dahurica Kitag (F)                   6.6 [+ or -] 0.59 *
Hierasiun procerum Fr (O)                     9.0 [+ or -] 0.15 *
Solonum nigra h. (St)                         8.4 [+ or -] 0.63 *
Agrimonia asiatica lus (R)                    6.8 [+ or -] 1.49 *
Xantium strumarium h.(R)                      6.5 [+ or -] 0.6 *
Cortusa turkestanica A. Los (F)               6.4 [+ or -] 0.5 *
Artemisia vilgaris L.(F)                      7.5 [+ or -] 1.04 *
Chamenerium angustibolium (L) Scop (R)        7.3 [+ or -] 0.23 *
Stachyopsys oblongata M. Popet Vved (O)       7.0 [+ or -] 0.31 *
Stachys betoniciflora Rupr (F)                7.0 [+ or -] 0.17 *
Ziziphora pedicillate Parii et Vved (St)      5.3 [+ or -] 0.075
Spiraea pilosa Franch (O)                     6.4 [+ or -] 0.87 *
Acroptilon repens (R)                         6.2 [+ or -] 0.4 *
Solonum nigra h. (R)                          7.4 [+ or -] 1.07 *
Phragmites communis Trin (St)                 6.9 [+ or -] 0.29 *
Cortusa turkestanica A. hos (R)               8.0 [+ or -] 0.46 *
Trigonella pamirica Boriss (A)                6.9 [+ or -] 0.76 *
Astragalus sp. (R)                            7.2 [+ or -] 0.55 *
Trifolium pratense L. (R)                     7.1 [+ or -] 1.31 *
Solonum nigra h. (L)                          7.3 [+ or -] 2.57 *
Pulicaria salviibolia Binge (St)              6.1 [+ or -] 1.18 *
Phragmites communis Tren (L)                  8.2 [+ or -] 0.57 *
Phragmites communis Trin (R)                 10.6 [+ or -] 1.1 *
Oberna beechen (L) Ikonn (Fr)                 9.8 [+ or -] 1.0 *
Agrimonia ariatica Ius (L)                   8.43 [+ or -] 1.0 *
Serophularia umbrosa Dumort (St)             8.63 [+ or -] 0.6 *
Serophularia umbrosa Dumort (O)              9.87 [+ or -] 0.8 *
Siderities montana L (St)                    8.43 [+ or -] 1.0 *
Phlomis olgae Rgl (R)                       10.17 [+ or -] 1.0 *
Serratula alatavica c.A.M. (F)               8.41 [+ or -] 1.6 *
Serratula alatavica c.A.M.(O)               10.14 [+ or -] 1.13 *
Inula helenium L (F)                         11.3 [+ or -] 0.6 *
Psoralea drupacea Bunge (R)                   8.9 [+ or -] 1.1 *
Inula helenium L (L)                          8.1 [+ or -] 0.8 *
Phlomis sewerzowii Rgl (O)                    8.3 [+ or -] 0.9 *

Note: F--flower; R- root; S--seed; FR--fruit; L--leaves; St--stem;
O--overground part; Sk--skin; E--entire plant; I--inflorescence;
A--upper part of overground part. Authentic difference P<0,05:
*--from intact group; **--from controlled
group.

TABLE 4. THE SCREENING OF VEGETABLE EXTRACTS ON PRESENCE OF ANTIOXIDANT
AND MEMBRANE STABILIZER EFFECT UNDER ETHANOL HYPERLIPIDEMIA

Name of Extracts                                   CP, mg/100 ml
       1                                               2

Intact group                                   16.0 [+ or -] 0.66
Controlled group                               10.3 [+ or -] 0.9
Plantago lanceolata (R)                        14.1 [+ or -] 3.13
Rosa canina (Sk)                               8.24 [+ or -] 1.18 *
Cratalgus songarica (R)                        6.36 [+ or -] 1.31 *
Cynodon dactulon (R)                           6.31 [+ or -] 2.17 *
Prunus sogdiana (R)                            8.84 [+ or -] 2.65 *
Rosa canina (R)                                8.63 [+ or -] 2.84 *
Crataegus pontica (L)                          5.79 [+ or -] 1.01 *
Luniperus zeravshanica (Fr)                     7.8 [+ or -] 0.69 *
Cynodon dactulon (O)                           6.65 [+ or -] 1.88 *
Rosa canina (Fr)                                6.1 [+ or -] 1.14 *
Picnomon acarna (O)                            8.43 [+ or -] 0.87 *
Alhagi pseudalhagi (R)                          8.1 [+ or -] 2.2 *
Rosa canina (L)                               12.12 [+ or -] 1.75 *
Prunus sogdiana (Fr)                           11.2 [+ or -] 3.4 *
Chenopodium album (Fr)                         8.81 [+ or -] 1.8 *
Rubus caesius (L)                              7.86 [+ or -] 1.9 *
Chenopodium album (R)                           6.5 [+ or -] 0.88 *
Amaranthus retroplexus (L)                      7.6 [+ or -] 1.65 *
Prunus sogdiana (L)                            5.36 [+ or -] 0.6 *
Amaranthus retroplexus (St)                    10.9 [+ or -] 1.4 *
Amaranthus retroplexus (Fr)                     7.8 [+ or -] 1.9 *
Prunus sogdiana (Sk)                            9.7 [+ or -] 1.08 *
Prunus sogdiana (R)                             6.5 [+ or -] 1.16 *
Prunus sogdiana (O)                             9.4 [+ or -] 2.28 *
Pheum Fedtshenokovi (F)                        10.9 [+ or -] 2.1 *
Atraphaxis pyrifolia (Sk)                      15.3 [+ or -] 0.56 **
Atraphaxis pyrifolia (St)                      13.6 [+ or -] 2.84 *
Atraphaxis pyrifolia (R)                       15.9 [+ or -] 1.88 **
Amygdalis spinosissima (S)                     12.3 [+ or -] 2.05 *
Cerasus erythrocapra (L)                        5.5 [+ or -] 0.81 *
Avena sativa (S)                               17.0 [+ or -] 0.7 **
Amygdalis bucharica (L)                        10.8 [+ or -] 1.8 *
Trifolium pratense (F)                         16.6 [+ or -] 1.5 **
Amygdalis bucharica (Sk)                       13.9 [+ or -] 1.96 *
Pheum Fedtshenokovi (L)                         6.2 [+ or -] 0.67 *
Amygdalis bucharica (L)                        10.7 [+ or -] 0.97 *
Trifolium repens (O)                            9.1 [+ or -] 2.36 *
Solidago dahurica Kitag (O)                     6.9 [+ or -] 1.22 *
Acroptilon repens (L)Op.(O)                     5.3 [+ or -] 0.9 *
Melandrium turkestanicus (Rgl)Vved (R)          7.9 [+ or -] 1.46 *
Inula helenium (R)                              4.6 [+ or -] 1.59 *
Artemisia vulgaris h. (O)                       7.2 [+ or -] 1.46 *
Berberis integerrima (Bge) (Fr)                 7.7 [+ or -] 0.7 *
Juniperus turkestanica Kom (L)                 15.9 [+ or -] 0.8 **
Solonum nigra h. (Fr)                           5.3 [+ or -] 1.51 *
Solidago dahurica kitag [R]                    6.98 [+ or -] 1.61 *
Melandrium turkestanicus (Rgl)Vved (O)         10.1 [+ or -] 1.8 *
Acroptilon repens (F)                           7.2 [+ or -] 2.61 *
Trifolim pratense h.(F)                         6.8 [+ or -] 0.84 *
Cousinia saawertziwii Regel (O)                 5.6 [+ or -] 1.46 *
Anaphalis Velutina Krasch (O)                   8.4 [+ or -] 2.11 *
Astragalus sp. (O)                              8.9 [+ or -] 1.77 *
Berberis oblonga (Rgl) Schneid [R]             10.7 [+ or -] 0.95 *
Hieracium procerum Fr [R]                       8.6 [+ or -] 2.05 *
Stachys betoniciflora rupr. [R]                 6.8 [+ or -] 1.16 *
Acantholimon erythraeum Bge (A)                15.6 [+ or -] 0.9 **
Pulicaria salviifolia Bunge (R)                10.7 [+ or -] 1.72 *
Psoralea drupacea Bunge (S)                    11.6 [+ or -] 2.97 *
Trifolim pratense h.(O)                         9.4 [+ or -] 0.63 *
Melandrium turkestanicus (Rgl)Vved (Fr)         6.4 [+ or -] 2.4 *
Artemisia vulgaris h. (R)                       9.4 [+ or -] 2.4 *
Descurania Sophia (L) Schur (Fr)               15.9 [+ or -] 1.23 **
Xantium strumarium h. (St)                      8.6 [+ or -] 0.33 *
Conum maculatum h. (St)                         9.8 [+ or -] 2.02 *
Cortusa turkestanica A.Los (O)                  6.8 [+ or -] 1.22 *
Tanasetopsis mucronatun S kovalev (O)          10.8 [+ or -] 1.59 *
Xantium strumarium h. (S)                       9.6 [+ or -] 1.29 *
Herniaria glabra h. (O)                        12.9 [+ or -] 1.99 *
Leonurus turkestanicusV.Krecr et Kupr (O)      12.4 [+ or -] 3.76 *
Arctium tomentisum Mill (R)                     8.3 [+ or -] 2.11 *
Ziziphora pedicillate Parii et Vved (R)         9.9 [+ or -] 1.53 *
Solidago dahurica Kitag (F)                     7.4 [+ or -] 1.44 *
Hierasiun procerum Fr (O)                      12.1 [+ or -] 2.65 *
Solonum nigra h. (St)                           7.3 [+ or -] 1.45 *
Agrimonia asiatica lus (R)                      5.9 [+ or -] 2.09 *
Xantium strumarium h.(R)                       12.3 [+ or -] 2.25 *
Cortusa turkestanica A. Los (F)                 7.7 [+ or -] 1.36 *
Artemisia vilgaris L.(F)                       12.4 [+ or -] 2.45 *
Chamenerium angustibolium (L) Scop (R)          8.5 [+ or -] 1.75 *
Stachyopsys oblongata M. Popet Vved (O)        13.6 [+ or -] 1.15
Stachys betoniciflora Rupr (F)                11.13 [+ or -] 2.2 *
Ziziphora pedicillate Parii et Vved (St)       12.2 [+ or -] 1.66 *
Spiraea pilosa Franch (O)                      11.8 [+ or -] 1.44 *
Acroptilon repens (R)                          11.6 [+ or -] 0.82 *
Solonum nigra h. (R)                            7.2 [+ or -] 3.43 *
Phragmites communis Trin (St)                   6.3 [+ or -] 1.4 *
Cortusa turkestanica A. hos (R)                10.9 [+ or -] 1.16 *
Trigonella pamirica Boriss (A)                 11.0 [+ or -] 2.31 *
Astragalus sp. (R)                             10.6 [+ or -] 0.75 *
Trifolium pratense L. (R)                       6.2 [+ or -] 0.39 *
Solonum nigra h. (L)                           11.0 [+ or -] 0.56 *
Pulicaria salviibolia Binge (St)               12.5 [+ or -] 2.0 *
Phragmites communis Tren (L)                   10.8 [+ or -] 1.43 *
Phragmites communis Trin (R)                   13.5 [+ or -] 2.9
Oberna beechen (L) Ikonn (Fr)                   9.4 [+ or -] 2.2 *
Agrimonia ariatica lus (L)                      6.8 [+ or -] 2.0 *
Serophularia umbrosa Dumort (St)               13.5 [+ or -] 2.6
Serophularia umbrosa Dumort (O)                11.9 [+ or -] 2.12 *
Siderities montana L (St)                      12.7 [+ or -] 3.3
Phlomis olgae Rgl (R)                          16.3 [+ or -] 2.04 **
Serratula alatavica c.A.M. (F)                 10.2 [+ or -] 2.3 *
Serratula alatavica c.A.M.(O)                  12.3 [+ or -] 3.64 *
Inula helenium L (F)                           11.3 [+ or -] 1.47 *
Psoralea drupacea Bunge (R)                     9.8 [+ or -] 1.68 *
Inula helenium L (L)                           12.8 [+ or -] 1.5 *
Phlomis sewerzowii Rgl (O)                     12.7 [+ or -] 4.89 *

Name of Extracts                                      PHE, %
       1                                               3

Intact group                                   11.3 [+ or -] 0.8
Controlled group                               17.1 [+ or -] 0.8
Plantago lanceolata (R)                        14.7 [+ or -] 0.71
Rosa canina (Sk)                               16.7 [+ or -] 0.5 *
Cratalgus songarica (R)                        14.9 [+ or -] 1.22 *
Cynodon dactulon (R)                           16.1 [+ or -] 0.5 *
Prunus sogdiana (R)                            15.0 [+ or -] 1.3 *
Rosa canina (R)                                15.4 [+ or -] 1.44 *
Crataegus pontica (L)                          15.6 [+ or -] 1.22 *
Luniperus zeravshanica (Fr)                    18.0 [+ or -] 1.1 *
Cynodon dactulon (O)                           15.7 [+ or -] 1.6 *
Rosa canina (Fr)                               17.1 [+ or -] 1.5 *
Picnomon acarna (O)                            12.8 [+ or -] 1.3 **
Alhagi pseudalhagi (R)                         13.3 [+ or -] 1.4
Rosa canina (L)                                12.0 [+ or -] 3.3 **
Prunus sogdiana (Fr)                           13.4 [+ or -] 0.9
Chenopodium album (Fr)                         15.2 [+ or -] 1.2 *
Rubus caesius (L)                              14.1 [+ or -] 1.91
Chenopodium album (R)                          13.2 [+ or -] 1.07
Amaranthus retroplexus (L)                     15.6 [+ or -] 2.36 *
Prunus sogdiana (L)                            14.3 [+ or -] 2.0
Amaranthus retroplexus (St)                    14.6 [+ or -] 2.9
Amaranthus retroplexus (Fr)                    14.4 [+ or -] 1.9
Prunus sogdiana (Sk)                           15.0 [+ or -] 2.2 *
Prunus sogdiana (R)                            15.0 [+ or -] 1.47 *
Prunus sogdiana (O)                            14.7 [+ or -] 0.87
Pheum Fedtshenokovi (F)                        13.4 [+ or -] 0.55
Atraphaxis pyrifolia (Sk)                      14.5 [+ or -] 1.45
Atraphaxis pyrifolia (St)                      14.5 [+ or -] 1.68
Atraphaxis pyrifolia (R)                       14.5 [+ or -] 0.3
Amygdalis spinosissima (S)                     16.6 [+ or -] 0.87 *
Cerasus erythrocapra (L)                       15.4 [+ or -] 0.41 *
Avena sativa (S)                               11.1 [+ or -] 1.2 **
Amygdalis bucharica (L)                        14.1 [+ or -] 1.35
Trifolium pratense (F)                         15.8 [+ or -] 1.04 *
Amygdalis bucharica (Sk)                       15.8 [+ or -] 0.82 *
Pheum Fedtshenokovi (L)                        16.5 [+ or -] 0.43 *
Amygdalis bucharica (L)                        15.9 [+ or -] 0.81 *
Trifolium repens (O)                           14.7 [+ or -] 0.75
Solidago dahurica Kitag (O)                    15.7 [+ or -] 2.44 *
Acroptilon repens (L)Op.(O)                    13.5 [+ or -] 1.87
Melandrium turkestanicus (Rgl)Vved (R)         13.3 [+ or -] 1.06
Inula helenium (R)                             14.1 [+ or -] 0.83
Artemisia vulgaris h. (O)                      14.1 [+ or -] 0.87
Berberis integerrima (Bge) (Fr)                16.3 [+ or -] 1.06 *
Juniperus turkestanica Kom (L)                 15.4 [+ or -] 0.88 *
Solonum nigra h. (Fr)                          15.7 [+ or -] 1.11 *
Solidago dahurica kitag [R]                    15.2 [+ or -] 2.21 *
Melandrium turkestanicus (Rgl)Vved (O)         15.6 [+ or -] 0.5 *
Acroptilon repens (F)                          13.6 [+ or -] 0.38
Trifolim pratense h.(F)                        17.7 [+ or -] 0.93 *
Cousinia saawertziwii Regel (O)                11.0 [+ or -] 0.75 **
Anaphalis Velutina Krasch (O)                  14.8 [+ or -] 1.31
Astragalus sp. (O)                             16.2 [+ or -] 1.16 *
Berberis oblonga (Rgl) Schneid [R]             14.8 [+ or -] 2.18
Hieracium procerum Fr [R]                      16.2 [+ or -] 0.97 *
Stachys betoniciflora rupr. [R]                15.6 [+ or -] 0.85 *
Acantholimon erythraeum Bge (A)                17.4 [+ or -] 0.45 *
Pulicaria salviifolia Bunge (R)                13.9 [+ or -] 1.07
Psoralea drupacea Bunge (S)                    15.1 [+ or -] 2.23 *
Trifolim pratense h.(O)                        16.1 [+ or -] 1.33 *
Melandrium turkestanicus (Rgl)Vved (Fr)        15.0 [+ or -] 2.26 *
Artemisia vulgaris h. (R)                      16.0 [+ or -] 0.91 *
Descurania Sophia (L) Schur (Fr)               16.3 [+ or -] 0.71 *
Xantium strumarium h. (St)                     14.9 [+ or -] 1.62
Conum maculatum h. (St)                        17.7 [+ or -] 3.25 *
Cortusa turkestanica A.Los (O)                 12.9 [+ or -] 0.75 **
Tanasetopsis mucronatun S kovalev (O)          14.9 [+ or -] 1.19
Xantium strumarium h. (S)                      13.6 [+ or -] 0.76
Herniaria glabra h. (O)                        13.5 [+ or -] 0.85
Leonurus turkestanicusV.Krecr et Kupr (O)      14.2 [+ or -] 1.91
Arctium tomentisum Mill (R)                    15.6 [+ or -] 1.14 *
Ziziphora pedicillate Parii et Vved (R)        11.9 [+ or -] 0.53 **
Solidago dahurica Kitag (F)                    14.4 [+ or -] 2.02
Hierasiun procerum Fr (O)                      13.5 [+ or -] 1.04
Solonum nigra h. (St)                          14.5 [+ or -] 1.98
Agrimonia asiatica lus (R)                     14.2 [+ or -] 1.69
Xantium strumarium h.(R)                       16.6 [+ or -] 0.53 *
Cortusa turkestanica A. Los (F)                16.1 [+ or -] 1.07 *
Artemisia vilgaris L.(F)                       14.9 [+ or -] 0.64
Chamenerium angustibolium (L) Scop (R)         12.3 [+ or -] 0.7 **
Stachyopsys oblongata M. Popet Vved (O)        14.5 [+ or -] 1.65
Stachys betoniciflora Rupr (F)                 13.7 [+ or -] 0.98
Ziziphora pedicillate Parii et Vved (St)       16.6 [+ or -] 1.73 *
Spiraea pilosa Franch (O)                      15.3 [+ or -] 1.28 *
Acroptilon repens (R)                          17.4 [+ or -] 1.12 *
Solonum nigra h. (R)                           14.2 [+ or -] 1.64
Phragmites communis Trin (St)                  15.3 [+ or -] 2.03 *
Cortusa turkestanica A. hos (R)                16.7 [+ or -] 1.54 *
Trigonella pamirica Boriss (A)                 13.1 [+ or -] 2.35
Astragalus sp. (R)                             14.2 [+ or -] 1.95
Trifolium pratense L. (R)                      17.1 [+ or -] 1.12 *
Solonum nigra h. (L)                           16.3 [+ or -] 2.66 *
Pulicaria salviibolia Binge (St)               16.3 [+ or -] 1.05 *
Phragmites communis Tren (L)                   14.3 [+ or -] 0.37
Phragmites communis Trin (R)                   16.5 [+ or -] 1.65 *
Oberna beechen (L) Ikonn (Fr)                  14.8 [+ or -] 1.42
Agrimonia ariatica lus (L)                     15.8 [+ or -] 2.15 *
Serophularia umbrosa Dumort (St)               16.0 [+ or -] 2.38 *
Serophularia umbrosa Dumort (O)                13.6 [+ or -] 0.89
Siderities montana L (St)                      15.1 [+ or -] 2.35 *
Phlomis olgae Rgl (R)                          16.4 [+ or -] 1.69 *
Serratula alatavica c.A.M. (F)                 14.8 [+ or -] 1.35
Serratula alatavica c.A.M.(O)                  15.1 [+ or -] 1.0 *
Inula helenium L (F)                           15.1 [+ or -] 2.5 *
Psoralea drupacea Bunge (R)                    14.2 [+ or -] 1.47
Inula helenium L (L)                           14.1 [+ or -] 1.0
Phlomis sewerzowii Rgl (O)                     14.1 [+ or -] 1.03

Note: F--flower; R- root; S--seed; FR--fruit; L--leaves; St--stem;
O--overground part; Sk--skin; E--entire plant; I--inflorescence;
A--upper part of overground part. Authentic difference P<0,05:
*--from intact group; **--from controlled group
COPYRIGHT 2011 Prague Development Center
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2011 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Author:Ziyaeva, Adolat; Yuldashev, Nosir
Publication:Medical and Health Science Journal
Geographic Code:9UZBE
Date:Jan 1, 2011
Words:13411
Previous Article:Comparative bioequivalence study of meloxicam drugs.
Next Article:Effect of "Stiflos" medication on the blood hemostasis in model of alimentary model.
Topics:

Terms of use | Privacy policy | Copyright © 2019 Farlex, Inc. | Feedback | For webmasters