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Indo-Mediterranean diet. (Clinical Capsules).

An Indo-Mediterranean diet rich in alphalinoleic acid, whole grains, legumes, fruits, vegetables, and nuts appears to be more effective in both primary and secondary prevention of coronary artery disease than the conventional Step 1 diet of the National Cholesterol Education Program, according to researchers at Moradabad (India) Medical Hospital and Research Centre.

They compared the diets in a 2-year study of Indian patients who either had established coronary artery disease or were at high risk. Two-thirds of the subjects were vegetarians; the rest ate meat once or twice a week. A total of 499 were randomly assigned to the Indo-Mediterranean diet and 501 to the NCEP Step 1 diet.

Compared with subjects on the NCEP diet, those on the Indo-Mediterranean diet had greater reductions in nonfatal MI, sudden cardiac death, and total cardiac events; consumed a greater percentage of calories from complex carbohydrates; had a higher polyunsaturated-to-saturated fat ratio; and had lower dietary total fat, saturated fat, and cholesterol levels (Lancet 360[9344]:1455-61, 2002).

Both groups had decreases in cholesterol and triglyceride levels, but the effect was larger in the Indo-Mediterranean group. That group also showed greater reductions in fasting blood glucose, body mass index, and blood pressure as well as a reduction in the number of patients requiring nitrates, verapamil, and disopyramide.

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Publication:Family Practice News
Article Type:Brief Article
Geographic Code:1USA
Date:Dec 15, 2002
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