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InSite Vision Names Tim McInerney Chairman of the Board.

ALAMEDA, Calif. -- InSite Vision Incorporated (OTCBB:INSV) today announced that Tim McInerney has been elected Chairman of its Board of Directors. Mr. McInerney has served as a member of the Board of Directors since 2008 and is Chairman of the Board's Nomination and Governance Committee as well as a member of the Board's Audit Committee.

Mr. McInerney has over 25 years of experience in both the investment and pharmaceutical industries. He is currently a partner with Riverbank Capital Securities, an investment banking firm that specializes in financing for biotechnology and specialty pharmaceutical companies. Mr. McInerney also serves on the boards of Edgemont Pharmaceuticals, LLC and Ziopharm Oncology, Inc.

"Tim is an outstanding Board member of InSite Vision who brings a wealth of seasoned business experience to our company and Board," said Timothy Ruane, Chief Executive Officer of InSite Vision. "I look forward to working even more closely with Tim in his new role as Board Chairman and welcome his guidance as we chart our path forward as an emerging leader in the global ophthalmology market."

InSite Vision has established a pipeline of innovative clinical- and preclinical-stage ophthalmic products leveraging the company's proven DuraSite([R]) drug delivery platform. The company is developing two Phase 3 product candidates for the treatment of blepharitis: AzaSite Plus([TM]) combines the corticosteroid dexamethasone 0.1% with the antibiotic azithromycin 1% in DuraSite; and DexaSite, which combines dexamethasone 0.1% with DuraSite. Another Phase 3 product candidate, BromSite([TM]) (previously ISV-303) (0.075% bromfenac in DuraSite), is in development for pain and inflammation associated with ocular surgery. In addition, InSite has ISV-101, which combines a low dose of bromfenac with DuraSite for the treatment of dry eye disease, ready for entry into a Phase 1/2 clinical trial.

About DuraSite([R])

InSite's DuraSite sustained delivery technology is a synthetic polymer-based formulation designed to extend the residence time of a drug relative to conventional topical therapies. It enables topical delivery of a solution, gel or suspension and can be customized for delivering a wide variety of potential drug candidates. The DuraSite platform is currently leveraged in two commercial products for the treatment of bacterial eye infections, AzaSite([R]) (azithromycin ophthalmic solution) 1% and Besivance([R]) (besifloxacin 0.6% ophthalmic suspension). InSite vision is applying DuraSite to multiple other clinical- and preclinical-stage product candidates to create a portfolio of novel ophthalmic products.

About InSite Vision

InSite Vision is advancing new and superior ophthalmologic products for unmet eye care needs. The company's product portfolio utilizes InSite Vision's proven DuraSite([R]) bioadhesive polymer core technology, an innovative platform that extends the duration of drug retention on the surface of the eye, thereby reducing frequency of treatment and improving the efficacy of topically delivered drugs. The DuraSite platform is currently leveraged in two commercial products for the treatment of bacterial eye infections, AzaSite([R]) (azithromycin ophthalmic solution) 1%, marketed in the U.S. by Merck, and Besivance([R]) (besifloxacin ophthalmic suspension) 0.6%, marketed by Bausch & Lomb and their partner Pfizer Inc. InSite Vision's clinical-stage ophthalmic product pipeline includes AzaSite Plus[TM] (ISV-502) and DexaSite[TM] (ISV-305) for the treatment of eye infections, BromSite([TM]) (ISV-303) for pain and swelling associated with ocular surgery, and ISV-101 for the treatment of dry eye disease. For further information on InSite Vision, please visit

Forward-looking Statements

This news release contains certain statements of a forward looking nature relating to future events, including InSite's strategy to become a new leader in the global ophthalmology market and InSite's plans for its DuraSite technology. Such statements entail a number of risks and uncertainties, including but not limited to: the results of clinical trials and the timing thereof; InSite's ability to obtain FDA approval for its product candidates and the timing thereof; InSite's reliance on third parties for the commercialization of its products; the ability of InSite to enter into corporate collaborations for its product candidates; InSite's ability to expand its product platform to include additional indications; InSite's ability to compete effectively, either alone or through its partners, with other companies offering competing products or treatments; InSite's ability to maintain and develop additional collaborations and commercial agreements with corporate partners, including those with respect to AzaSite; its ability to adequately protect its intellectual property and to be free to operate with regard to the intellectual property of others; and determinations by the FDA. Reference is made to the discussion of these and other risk factors detailed in InSite Vision's filings with the Securities and Exchange Commission, including its annual report on Form 10-K and its quarterly reports on Form 10-Q, under the caption "Risk Factors" and elsewhere in such reports. Any forward-looking statements or projections are based on the limited information currently available to InSite Vision, which is subject to change. Although any such forward-looking statements or projections and the factors influencing them will likely change, InSite Vision undertakes no obligation to update the information. Such information speaks only as of the date of its release. Actual events or results could differ materially and one should not assume that the information provided in this release is still valid at any later date.

AzaSite([R]) and DuraSite([R])are registered trademarks of InSite Vision Incorporated.

BESIVANCE([R]) is a registered trademark of Bausch & Lomb Incorporated.
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Comment:InSite Vision Names Tim McInerney Chairman of the Board.
Publication:Business Wire
Geographic Code:1U9CA
Date:Dec 19, 2011
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