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In an unexpected finding, researchers have linked the activation of a stress gene in immune-system cells to the spread of breast cancer to other parts of the body..

In an unexpected finding, researchers have linked the activation of a stress gene in immune-system cells to the spread of breast cancer to other parts of the body. Scientists say the study suggests this gene, called ATF3, may be the crucial link between stress and cancer, including the major cause of cancer death--its spread, or metastasis. Previous public health studies have shown that stress is a risk factor for cancer. This research, published in the Journal of Clinical Investigation, suggests that cancer cells somehow coax immune-system cells that have been recruited to the site of a tumor to express ATF3, although it still is unclear how ATF3 promotes the immune cells to act erratically and give cancer an escape route from a tumor to other areas of the body.

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Title Annotation:HEALTH BEAT; ATF3 gene
Publication:USA Today (Magazine)
Article Type:Brief article
Geographic Code:1USA
Date:Oct 1, 2014
Words:129
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