Immunology study finds decreased activation markers related to better viral control.
Comment: This is a kind of study that has been needed for a long time, to measure immune changes in patients and correlate them with virologic and/or clinical outcomes. These studies can be done in children because, for political reasons and also due to the success of preventing maternal transmission, the amount of money for AIDS research for children is disproportionate to the number of U.S. cases. Immunological studies in patients have lagged far behind antiviral studies, since there is little commercial interest in them, as there are no approved immune treatments for HIV infection. Fortunately this study could be done because one political influence on research helped to correct another.
Reference: Rosenblatt HM, Stanley KE, Song LY and others. Immunological response to highly active antiretroviral therapy in children with clinically stable HIV-1 infection. Journal of Infectious Diseases. August l, 2005; volume 192, number 3, pages 445-455.
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|Author:||James, John S.|
|Publication:||AIDS Treatment News|
|Date:||Jun 24, 2005|
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