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IMMUNOMEDICS AWARDED BROAD U.S. PATENT ON ORGAN IMAGING; METHOD COVERS IMAGING OF NORMAL ORGANS AND THE IDENTIFICATION OF DISEASED TISSUES

IMMUNOMEDICS AWARDED BROAD U.S. PATENT ON ORGAN IMAGING; METHOD COVERS IMAGING OF NORMAL ORGANS AND THE IDENTIFICATION OF DISEASED TISSUES
 WARREN, N.J., April 7 /PRNewswire/ -- Immunomedics, Inc. (NASDAQ: IMMU), today announced the issuance of U.S. Patent No. 5,101,827. The patent claims methods for imaging normal organs as well as methods for imaging lymph nodes to determine the presence of tumors or infectious lesions.
 In the patented methods, normal organs or lymph nodes are imaged using scintigraphic or magnetic resonance imaging techniques. The patient is injected with a labeled antibody or antibody fragment; the label is a radioisotope or a magnetic resonance image-enhancing agent, which binds with the organ or lymph node. After the labeled antibody or antibody fragment has been allowed to accrete in the organ or lymph node, an image is taken. The patented method makes it possible to obtain a "positive" image of the organ or lymph node showing the structure's size and shape. Missing or pathological areas show up as defects or "cold spots".
 It is important in certain clinical situations to be able to determine whether an organ or lymph node is present and anatomically correct and whether the organ or lymph node has a pathological condition, e.g., obstruction, infection, neoplasia, etc. Using the patented methods, a clinician can make these determinations by a non- invasive technique.
 David M. Goldenberg, the inventor, commented, "This technique holds promise
to contribute to radiological diagnosis. For example, a breast or prostate cancer patient's bone marrow could be imaged with a radiolabeled antibody, such as Immunomedics' MN3, which is specific to certain white blood cells. In the resulting positive image of the patient's bone marrow, cold spots could indicate cancer as a result of metastasis, or spread, from the breast or prostate cancer to the bone marrow." MN3, for infectious diseases, is presently in Phase I/II clinical trials prior to a submission of a Product License Application (PLA) to the Food and Drug Administration.
 Immunomedics has rights under 22 issued U.S. patents and over 200 patents and applications filed worldwide.
 Immunomedics is a biopharmaceutical company applying innovative technology in antibody selection, modification and chemistry to the development of products for the detection and treatment of cancer and infectious diseases. Integral to these products are highly specific monoclonal antibodies designed to deliver radioisotopes, chemotherapuetic agents or toxins to tumors and sites of infections or other diseases.
 -0- 4/7/92
 /CONTACT: Amy Factor of Immunomedics, 908-647-5400/
 (IMMU) CO: Immunomedics, Inc. ST: New Jersey IN: MTC SU:


GK-TS -- NY019 -- 5728 04/07/92 09:47 EDT
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Publication:PR Newswire
Date:Apr 7, 1992
Words:432
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