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IBS in Twins. (Clinical Capsules).

The likelihood that someone will develop irritable bowel syndrome is influenced as much by social learning as by genetics, reported Rona L. Levy Ph.D., of the University of Washington, Seattle, and her associates.

Irritable bowel syndrome (IBS) was reported by 117 pairs of monozygotic twins and 164 pairs of dizygotic twins on questionnaires completed by 6,060 twin pairs living in Virginia. The mothers of 2% of all respondents also had IBS, including the mothers of 15% of the dizygotic and 17% of the monozygotic twins with IBS.

The probability that a dizygotic twin with IBS would have a mother with IBS was greater than the chance that the twin would have a cotwin with IBS (Gastroenterology 121[4]:799-804, 2001).

Mothers share the same number of genes with their children as dizygotic twins share with each other. However, the proportion of dizygotic twins who have IBS and a mother with IBS is significantly greater than the proportion of dizygotic twins with IBS who have a cotwin with IBS.

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Publication:Family Practice News
Article Type:Brief Article
Geographic Code:1USA
Date:Dec 15, 2001
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