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Herpes zoster; recent aspects of diagnosis and control.


Herpes zoster; recent aspects of diagnosis and control.

Ed. by Gerd Gross and Hans-Wilhelm Doerr.

S. Karger, AG


193 pages



Monographs in virology; v.26


Herpes zoster (shingles) is nearly always caused by the reactivation of the latent or waning varicella-zoster virus (VZV). Although younger people are sometimes affected, those over age 50 are most likely to suffer the agony of herpes zoster, and it strikes deeply into the population over 80. Those whose immune systems have been repressed, such as those receiving bone marrow transplants, are also in danger. In response, the contributors of these 17 articles present current strategies for diagnosing, treating and preventing herpes zoster, addressing such topics as the molecular biology of VZVG and its latency and reactivation, laboratory confirmation, infections from the point of view of the dermatologist and ophthalmologist, identification of zoster oticus, pain and neuropathology, VZV in pregnancy and in a host with compromised immunity, and chickenpox and zoster in a marrow transplant recipient. Therapies described include antiviral bicyclic furo[2,3-d] pyrimidine nucleoside analogues, and pain therapy. Particularly interesting are articles on what has changed about herpes zoster and the possibility of a live-attenuated vaccine.

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Publication:SciTech Book News
Article Type:Book Review
Date:Dec 1, 2006
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