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Herbal extract promotes proliferation of endogenous neural stem cells.

WEIFANG, China, July 23, 2013 -- Neural stem cells proliferate in the subventricular zone and hippocampal dentate gyrus of adult mammals.

However, the number of endogenous neural stem cells is insufficient to prevent cerebral ischemia/ reperfusion injuries such as vascular dementia, so it is important to stimulate endogenous neural stem cell proliferation and differentiation.

Researchers here have shown that ginkgo biloba extract EGb761 effectively and safely treats memory loss and cognitive impairments in patients with senile dementia.

Prof. Yuliang Wang and team from Weifang Medical University observed the effects of EGb761 on proliferation of neural stem cells in the subventricular zone and dentate gyrus of rats with vascular dementia.

Researchers found that the ginkgo biloba extract EGb761 promoted and prolonged the proliferation of neural stem cells in the subventricular zone and dentate gyrus of rats with vascular dementia.

The cells continued to proliferate at four months. EGb761 also significantly improved learning and memory in rats with vascular dementia.

Citation: "A ginkgo biloba extract promotes proliferation of endogenous neural stem cells in vascular dementia rats"; Wang J W et al.; Neural Regeneration Research, 2013; 8 (18): 1655-1662 DOI: 10.3969/j.issn.1673-5374.2013.18.003

Abstract: http://dx.doi.org/10.3969/j.issn.1673-5374.2013.18.003

Contact: Yuliang Wang, wangyl@wfmc.edu.cn

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Title Annotation:Preclinical Research
Publication:Stem Cell Research News
Date:Aug 5, 2013
Words:214
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